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The Role of Pumilio RNA Binding Protein in Plants
Eukaryotic organisms have a posttranscriptional/translational regulation system for the control of translational efficiency. RNA binding proteins (RBPs) have been known to control target genes. One type of protein, Pumilio (Pum)/Puf family RNA binding proteins, show a specific binding of 3′ untransl...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699478/ https://www.ncbi.nlm.nih.gov/pubmed/34944494 http://dx.doi.org/10.3390/biom11121851 |
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author | Huh, Sung Un |
author_facet | Huh, Sung Un |
author_sort | Huh, Sung Un |
collection | PubMed |
description | Eukaryotic organisms have a posttranscriptional/translational regulation system for the control of translational efficiency. RNA binding proteins (RBPs) have been known to control target genes. One type of protein, Pumilio (Pum)/Puf family RNA binding proteins, show a specific binding of 3′ untranslational region (3′ UTR) of target mRNA and function as a post-transcriptional/translational regulator in eukaryotic cells. Plant Pum protein is involved in development and biotic/abiotic stresses. Interestingly, Arabidopsis Pum can control target genes in a sequence-specific manner and rRNA processing in a sequence-nonspecific manner. As shown in in silico Pum gene expression analysis, Arabidopsis and rice Pum genes are responsive to biotic/abiotic stresses. Plant Pum can commonly contribute to host gene regulation at the post-transcriptional/translational step, as can mammalian Pum. However, the function of plant Pum proteins is not yet fully known. In this review, we briefly summarize the function of plant Pum in defense, development, and environmental responses via recent research and bioinformatics data. |
format | Online Article Text |
id | pubmed-8699478 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86994782021-12-24 The Role of Pumilio RNA Binding Protein in Plants Huh, Sung Un Biomolecules Review Eukaryotic organisms have a posttranscriptional/translational regulation system for the control of translational efficiency. RNA binding proteins (RBPs) have been known to control target genes. One type of protein, Pumilio (Pum)/Puf family RNA binding proteins, show a specific binding of 3′ untranslational region (3′ UTR) of target mRNA and function as a post-transcriptional/translational regulator in eukaryotic cells. Plant Pum protein is involved in development and biotic/abiotic stresses. Interestingly, Arabidopsis Pum can control target genes in a sequence-specific manner and rRNA processing in a sequence-nonspecific manner. As shown in in silico Pum gene expression analysis, Arabidopsis and rice Pum genes are responsive to biotic/abiotic stresses. Plant Pum can commonly contribute to host gene regulation at the post-transcriptional/translational step, as can mammalian Pum. However, the function of plant Pum proteins is not yet fully known. In this review, we briefly summarize the function of plant Pum in defense, development, and environmental responses via recent research and bioinformatics data. MDPI 2021-12-09 /pmc/articles/PMC8699478/ /pubmed/34944494 http://dx.doi.org/10.3390/biom11121851 Text en © 2021 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Huh, Sung Un The Role of Pumilio RNA Binding Protein in Plants |
title | The Role of Pumilio RNA Binding Protein in Plants |
title_full | The Role of Pumilio RNA Binding Protein in Plants |
title_fullStr | The Role of Pumilio RNA Binding Protein in Plants |
title_full_unstemmed | The Role of Pumilio RNA Binding Protein in Plants |
title_short | The Role of Pumilio RNA Binding Protein in Plants |
title_sort | role of pumilio rna binding protein in plants |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699478/ https://www.ncbi.nlm.nih.gov/pubmed/34944494 http://dx.doi.org/10.3390/biom11121851 |
work_keys_str_mv | AT huhsungun theroleofpumiliornabindingproteininplants AT huhsungun roleofpumiliornabindingproteininplants |