Cargando…

The Role of Pumilio RNA Binding Protein in Plants

Eukaryotic organisms have a posttranscriptional/translational regulation system for the control of translational efficiency. RNA binding proteins (RBPs) have been known to control target genes. One type of protein, Pumilio (Pum)/Puf family RNA binding proteins, show a specific binding of 3′ untransl...

Descripción completa

Detalles Bibliográficos
Autor principal: Huh, Sung Un
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699478/
https://www.ncbi.nlm.nih.gov/pubmed/34944494
http://dx.doi.org/10.3390/biom11121851
_version_ 1784620522850484224
author Huh, Sung Un
author_facet Huh, Sung Un
author_sort Huh, Sung Un
collection PubMed
description Eukaryotic organisms have a posttranscriptional/translational regulation system for the control of translational efficiency. RNA binding proteins (RBPs) have been known to control target genes. One type of protein, Pumilio (Pum)/Puf family RNA binding proteins, show a specific binding of 3′ untranslational region (3′ UTR) of target mRNA and function as a post-transcriptional/translational regulator in eukaryotic cells. Plant Pum protein is involved in development and biotic/abiotic stresses. Interestingly, Arabidopsis Pum can control target genes in a sequence-specific manner and rRNA processing in a sequence-nonspecific manner. As shown in in silico Pum gene expression analysis, Arabidopsis and rice Pum genes are responsive to biotic/abiotic stresses. Plant Pum can commonly contribute to host gene regulation at the post-transcriptional/translational step, as can mammalian Pum. However, the function of plant Pum proteins is not yet fully known. In this review, we briefly summarize the function of plant Pum in defense, development, and environmental responses via recent research and bioinformatics data.
format Online
Article
Text
id pubmed-8699478
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-86994782021-12-24 The Role of Pumilio RNA Binding Protein in Plants Huh, Sung Un Biomolecules Review Eukaryotic organisms have a posttranscriptional/translational regulation system for the control of translational efficiency. RNA binding proteins (RBPs) have been known to control target genes. One type of protein, Pumilio (Pum)/Puf family RNA binding proteins, show a specific binding of 3′ untranslational region (3′ UTR) of target mRNA and function as a post-transcriptional/translational regulator in eukaryotic cells. Plant Pum protein is involved in development and biotic/abiotic stresses. Interestingly, Arabidopsis Pum can control target genes in a sequence-specific manner and rRNA processing in a sequence-nonspecific manner. As shown in in silico Pum gene expression analysis, Arabidopsis and rice Pum genes are responsive to biotic/abiotic stresses. Plant Pum can commonly contribute to host gene regulation at the post-transcriptional/translational step, as can mammalian Pum. However, the function of plant Pum proteins is not yet fully known. In this review, we briefly summarize the function of plant Pum in defense, development, and environmental responses via recent research and bioinformatics data. MDPI 2021-12-09 /pmc/articles/PMC8699478/ /pubmed/34944494 http://dx.doi.org/10.3390/biom11121851 Text en © 2021 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Huh, Sung Un
The Role of Pumilio RNA Binding Protein in Plants
title The Role of Pumilio RNA Binding Protein in Plants
title_full The Role of Pumilio RNA Binding Protein in Plants
title_fullStr The Role of Pumilio RNA Binding Protein in Plants
title_full_unstemmed The Role of Pumilio RNA Binding Protein in Plants
title_short The Role of Pumilio RNA Binding Protein in Plants
title_sort role of pumilio rna binding protein in plants
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699478/
https://www.ncbi.nlm.nih.gov/pubmed/34944494
http://dx.doi.org/10.3390/biom11121851
work_keys_str_mv AT huhsungun theroleofpumiliornabindingproteininplants
AT huhsungun roleofpumiliornabindingproteininplants