Metformin Treatment or PRODH/POX-Knock out Similarly Induces Apoptosis by Reprograming of Amino Acid Metabolism, TCA, Urea Cycle and Pentose Phosphate Pathway in MCF-7 Breast Cancer Cells

It has been considered that proline dehydrogenase/proline oxidase (PRODH/POX) is involved in antineoplastic activity of metformin (MET). The aim of this study is identification of key metabolites of glycolysis, pentose phosphate pathway (PPP), tricarboxylic acids (TCA), urea cycles (UC) and some ami...

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Detalles Bibliográficos
Autores principales: Huynh, Thi Yen Ly, Oscilowska, Ilona, Sáiz, Jorge, Nizioł, Magdalena, Baszanowska, Weronika, Barbas, Coral, Palka, Jerzy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699520/
https://www.ncbi.nlm.nih.gov/pubmed/34944532
http://dx.doi.org/10.3390/biom11121888

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