Cargando…

Activation of the alpha 7 nicotinic acetylcholine receptor mitigates osteoarthritis progression by inhibiting NF-κB/NLRP3 inflammasome activation and enhancing autophagy

Osteoarthritis (OA) is a chronic degenerative joint disease characterized by cartilage degradation. Alpha 7 nicotinic acetylcholine receptor (α7nAChR) is associated with inflammatory and metabolic responses in OA. However, the mechanisms underlying the pathological process of OA remain unclear. The...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Xianjie, Dai, Shiyou, Xia, Baohua, Gong, Jianbao, Ma, Bingzheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699641/
https://www.ncbi.nlm.nih.gov/pubmed/34941874
http://dx.doi.org/10.1371/journal.pone.0256507

Ejemplares similares