Viral surface geometry shapes influenza and coronavirus spike evolution through antibody pressure

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The evolution of circulating viruses is shaped by their need to evade antibody response, which mainly targets the viral spike. Because of the high density of spikes on the viral surface, not all antigenic sites are targeted equally by antibodies. We offer here a geometry-based approach to predict an...

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Detalles Bibliográficos
Autor principal: Amitai, Assaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699686/
https://www.ncbi.nlm.nih.gov/pubmed/34898597
http://dx.doi.org/10.1371/journal.pcbi.1009664
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