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Oligomeric States and Hydrodynamic Properties of Lysyl Oxidase-Like 2

Lysyl oxidase-like 2 (LOXL2) has emerged as a promising therapeutic target against metastatic/invasive tumors and organ and tissue fibrosis. LOXL2 catalyzes the oxidative deamination of lysine and hydroxylysine residues in extracellular matrix (ECM) proteins to promote crosslinking of these proteins...

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Detalles Bibliográficos
Autores principales: Meier, Alex A., Moon, Hee-Jung, Toth, Ronald, Folta-Stogniew, Ewa, Kuczera, Krzysztof, Middaugh, C. Russell, Mure, Minae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699698/
https://www.ncbi.nlm.nih.gov/pubmed/34944490
http://dx.doi.org/10.3390/biom11121846