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Oligomeric States and Hydrodynamic Properties of Lysyl Oxidase-Like 2
Lysyl oxidase-like 2 (LOXL2) has emerged as a promising therapeutic target against metastatic/invasive tumors and organ and tissue fibrosis. LOXL2 catalyzes the oxidative deamination of lysine and hydroxylysine residues in extracellular matrix (ECM) proteins to promote crosslinking of these proteins...
Autores principales: | Meier, Alex A., Moon, Hee-Jung, Toth, Ronald, Folta-Stogniew, Ewa, Kuczera, Krzysztof, Middaugh, C. Russell, Mure, Minae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699698/ https://www.ncbi.nlm.nih.gov/pubmed/34944490 http://dx.doi.org/10.3390/biom11121846 |
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