Cargando…

H(2)S Donors and Their Use in Medicinal Chemistry

Hydrogen sulfide (H(2)S) is a ubiquitous gaseous signaling molecule that has an important role in many physiological and pathological processes in mammalian tissues, with the same importance as two others endogenous gasotransmitters such as NO (nitric oxide) and CO (carbon monoxide). Endogenous H(2)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Magli, Elisa, Perissutti, Elisa, Santagada, Vincenzo, Caliendo, Giuseppe, Corvino, Angela, Esposito, Gianluca, Esposito, Giovanna, Fiorino, Ferdinando, Migliaccio, Marco, Scognamiglio, Antonia, Severino, Beatrice, Sparaco, Rosa, Frecentese, Francesco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699746/ https://www.ncbi.nlm.nih.gov/pubmed/34944543 http://dx.doi.org/10.3390/biom11121899

Ejemplares similares

Trends in H(2)S-Donors Chemistry and Their Effects in Cardiovascular Diseases
por: Corvino, Angela, et al.
Publicado: (2021)

Design, Synthesis and Evaluation of Novel Molecular Hybrids between Antiglaucoma Drugs and H(2)S Donors
por: Sparaco, Rosa, et al.
Publicado: (2022)

Synthesis, Chiral Resolution and Enantiomers Absolute Configuration of 4-Nitropropranolol and 7-Nitropropranolol
por: Sparaco, Rosa, et al.
Publicado: (2022)

Design, Synthesis and Biological Evaluation of Novel N-Arylpiperazines Containing a 4,5-Dihydrothiazole Ring
por: Andreozzi, Giorgia, et al.
Publicado: (2023)

New Insights into the Structure–Activity Relationship and Neuroprotective Profile of Benzodiazepinone Derivatives of Neurounina-1 as Modulators of the Na(+)/Ca(2+) Exchanger Isoforms
por: Magli, Elisa, et al.
Publicado: (2021)

Fragment-based de novo design of a cystathionine γ-lyase selective inhibitor blocking hydrogen sulfide production
por: Corvino, Angela, et al.
Publicado: (2016)

Structure-activity relationships study of isothiocyanates for H(2)S releasing properties: 3-Pyridyl-isothiocyanate as a new promising cardioprotective agent
por: Citi, Valentina, et al.
Publicado: (2020)

Synthesis and Pharmacological Screening of Pyridopyrimidines as Effective Anti‐Diarrheal Agents through the Suppression of Cyclic Nucleotide Accumulation
por: Zaminelli, Tiago, et al.
Publicado: (2019)

Development of 1,2,3-Triazole-Based Sphingosine Kinase Inhibitors and Their Evaluation as Antiproliferative Agents
por: Corvino, Angela, et al.
Publicado: (2017)

Antagonizing S1P(3) Receptor with Cell-Penetrating Pepducins in Skeletal Muscle Fibrosis
por: Corvino, Angela, et al.
Publicado: (2021)

Synthesis, Docking Studies and Pharmacological Evaluation of Serotoninergic Ligands Containing a 5-Norbornene-2-Carboxamide Nucleus
por: Sparaco, Rosa, et al.
Publicado: (2022)

Development, Validation of LC-MS/MS Method and Determination of Pharmacokinetic Parameters of the Stroke Neuroprotectant Neurounina-1 in Beagle Dog Plasma After Intravenous Administration
por: Severino, Beatrice, et al.
Publicado: (2019)

Serotoninergic receptor ligands improve Tamoxifen effectiveness on breast cancer cells
por: Ambrosio, Maria Rosaria, et al.
Publicado: (2022)

H(2)S donating corticosteroids: Design, synthesis and biological evaluation in a murine model of asthma
por: Corvino, Angela, et al.
Publicado: (2021)

Anti-metastatic Properties of Naproxen-HBTA in a Murine Model of Cutaneous Melanoma
por: Ercolano, Giuseppe, et al.
Publicado: (2019)

Beneficial Effects of Two Hydrogen Sulfide (H(2)S)-Releasing Derivatives of Dexamethasone with Antioxidant Activity on Atopic Dermatitis in Mice
por: Coavoy-Sánchez, Silvia Abigail, et al.
Publicado: (2023)

The Application of Microwaves, Ultrasounds, and Their Combination in the Synthesis of Nitrogen-Containing Bicyclic Heterocycles
por: Frecentese, Francesco, et al.
Publicado: (2023)

Prednisone-hydrogen sulfide releasing hybrid shows improved therapeutic profile in asthma
por: Cerqua, Ida, et al.
Publicado: (2023)

Synthesis, in vitro and in vivo evaluation of (11)C-O-methylated arylpiperazines as potential serotonin 1A (5-HT(1A)) receptor antagonist radiotracers
por: Narayanaswami, Vidya, et al.
Publicado: (2020)

Phloroglucinol-Derived Medications are Effective in Reducing Pain and Spasms of Urinary and Biliary Tracts: Results of Phase 3 Multicentre, Open-Label, Randomized, Comparative Studies of Clinical Effectiveness and Safety
por: Corvino, Angela, et al.
Publicado: (2022)

Fully Automated Synthesis of Novel TSPO PET Imaging Ligand [(18)F]Fluoroethyltemazepam
por: Fiorenza, Dario, et al.
Publicado: (2021)

Multifaceted Aspects of HIV-1 Nucleocapsid Inhibition by TAR-Targeting Peptidyl-Anthraquinones Bearing Terminal Aromatic Moieties
por: Sosic, Alice, et al.
Publicado: (2022)

Clinical and surgical data of affected members of a classic CFEOM 1 family
por: Magli, Adriano, et al.
Publicado: (2003)

Thermodynamic efficiency in dissipative chemistry
por: Penocchio, Emanuele, et al.
Publicado: (2019)

Long-term development of refractive error in refractive, nonrefractive and partially accommodative esotropia
por: Esposito Veneruso, Paolo, et al.
Publicado: (2018)

Na(+)/Ca(2+) exchanger isoform 1 takes part to the Ca(2+)-related prosurvival pathway of SOD1 in primary motor neurons exposed to beta-methylamino-l-alanine
por: Petrozziello, Tiziana, et al.
Publicado: (2022)

Long-Term Effects of Botulinum Toxin in Large-Angle Infantile Esotropia
por: Gallo, Flavio Gioele, et al.
Publicado: (2020)

“Traditional” Sol-Gel Chemistry as a Powerful Tool for the Preparation of Supported Metal and Metal Oxide Catalysts
por: Esposito, Serena
Publicado: (2019)

ROS-Mediated Apoptotic Cell Death of Human Colon Cancer LoVo Cells by Milk δ-Valerobetaine
por: D’Onofrio, Nunzia, et al.
Publicado: (2020)

Donor and Recipient Outcomes following Robotic-Assisted Laparoscopic Living Donor Nephrectomy: A Systematic Review
por: Creta, Massimiliano, et al.
Publicado: (2019)

Identification of Potential Allelochemicals From Donor Plants and Their Synergistic Effects on the Metabolome of Aegilops geniculata
por: Scognamiglio, Monica, et al.
Publicado: (2020)

Chemical Composition and Seasonality of Aromatic Mediterranean Plant Species by NMR-Based Metabolomics
por: Scognamiglio, Monica, et al.
Publicado: (2015)

Fructose and Uric Acid: Major Mediators of Cardiovascular Disease Risk Starting at Pediatric Age
por: Russo, Elisa, et al.
Publicado: (2020)

Prenylated phloroglucinols from Hypericum scruglii, an endemic species of Sardinia (Italy), as new dual HIV-1 inhibitors effective on HIV-1 replication
por: Sanna, Cinzia, et al.
Publicado: (2018)

Long-term effects of early/late-onset visual deprivation on macular and retinal nerve fibers layer structure: A pilot study
por: Magli, Adriano, et al.
Publicado: (2023)

Effect of Gaseous Citral on Table Grapes Contaminated by Rhizopus oryzae ITEM 18876
por: Quintieri, Laura, et al.
Publicado: (2022)

Femoral herniation of transplanted ureter after deceased-donor kidney transplantation
por: Esposito, Matthew, et al.
Publicado: (2015)

The importance of pollen chemistry in evolutionary host shifts of bees
por: Vanderplanck, Maryse, et al.
Publicado: (2017)

Prebiotic Chemistry that Could Not Not Have Happened
por: Benner, Steven A., et al.
Publicado: (2019)

Daratumumab in the treatment of C3 glomerulopathy with monoclonal gammopathy: a case report and literature review
por: Esposito, Pasquale, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_j3cnlcs0a6ivadnhputv2afdsa