Synthesis of Human Bone Morphogenetic Protein-2 (hBMP-2) in E. coli Periplasmic Space: Its Characterization and Preclinical Testing

Human BMP-2, a homodimeric protein that belongs to the TGF- β family, is a recognized osteoinductor due to its capacity of inducing bone regeneration and ectopic bone formation. The administration of its recombinant form is an alternative to autologous bone grafting. A variety of E. coli-derived hBM...

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Detalles Bibliográficos
Autores principales: Oliveira, João E., Suzuki, Miriam F., Damiani, Renata, Lima, Eliana R., Amaral, Kleicy C., Santos, Anderson M. S., Magalhães, Geraldo S., Faverani, Leonardo P., Pereira, Luís A. V. D., Bartolini, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699916/
https://www.ncbi.nlm.nih.gov/pubmed/34944033
http://dx.doi.org/10.3390/cells10123525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699916/
https://www.ncbi.nlm.nih.gov/pubmed/34944033
http://dx.doi.org/10.3390/cells10123525

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