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Synthesis of Human Bone Morphogenetic Protein-2 (hBMP-2) in E. coli Periplasmic Space: Its Characterization and Preclinical Testing
Human BMP-2, a homodimeric protein that belongs to the TGF- β family, is a recognized osteoinductor due to its capacity of inducing bone regeneration and ectopic bone formation. The administration of its recombinant form is an alternative to autologous bone grafting. A variety of E. coli-derived hBM...
Autores principales: | Oliveira, João E., Suzuki, Miriam F., Damiani, Renata, Lima, Eliana R., Amaral, Kleicy C., Santos, Anderson M. S., Magalhães, Geraldo S., Faverani, Leonardo P., Pereira, Luís A. V. D., Bartolini, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699916/ https://www.ncbi.nlm.nih.gov/pubmed/34944033 http://dx.doi.org/10.3390/cells10123525 |
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