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Emerging Molecular Dependencies of Mutant EGFR-Driven Non-Small Cell Lung Cancer

Epidermal growth factor receptor (EGFR) mutations are the molecular driver of a subset of non-small cell lung cancers (NSCLC); tumors that harbor these mutations are often dependent on sustained oncogene signaling for survival, a concept known as “oncogene addiction”. Inhibiting EGFR with tyrosine k...

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Detalles Bibliográficos
Autores principales: Farnsworth, Dylan A., Chen, Yankuan T., de Rappard Yuswack, Georgia, Lockwood, William W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699920/
https://www.ncbi.nlm.nih.gov/pubmed/34944063
http://dx.doi.org/10.3390/cells10123553

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