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Epidemiological characteristics of COVID-19 travel-associated cases in Vojvodina, Serbia, during 2020

Coronavirus disease 2019 (COVID-19) is currently the biggest public health problem worldwide. Intensive international travel and tourism have greatly contributed to its rapid global spreading. This study is the first comprehensive analysis of the epidemiological characteristics and clinical outcomes...

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Autores principales: Pustahija, Tatjana, Ristić, Mioljub, Medić, Snežana, Vuković, Vladimir, Štrbac, Mirjana, Rajčević, Smiljana, Patić, Aleksandra, Petrović, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699980/
https://www.ncbi.nlm.nih.gov/pubmed/34941947
http://dx.doi.org/10.1371/journal.pone.0261840
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author Pustahija, Tatjana
Ristić, Mioljub
Medić, Snežana
Vuković, Vladimir
Štrbac, Mirjana
Rajčević, Smiljana
Patić, Aleksandra
Petrović, Vladimir
author_facet Pustahija, Tatjana
Ristić, Mioljub
Medić, Snežana
Vuković, Vladimir
Štrbac, Mirjana
Rajčević, Smiljana
Patić, Aleksandra
Petrović, Vladimir
author_sort Pustahija, Tatjana
collection PubMed
description Coronavirus disease 2019 (COVID-19) is currently the biggest public health problem worldwide. Intensive international travel and tourism have greatly contributed to its rapid global spreading. This study is the first comprehensive analysis of the epidemiological characteristics and clinical outcomes of the travel-associated COVID-19 cases in Vojvodina, Serbia, from March 6 to December 31, 2020 and it concerns permanent residents of Serbia. A cross-sectional study was conducted using data from the dedicated surveillance database of the Institute of Public Health of Vojvodina. Overall, 650 travel-associated COVID-19 cases were recorded in Vojvodina during the observed period, mainly imported from Bosnia and Herzegovina, followed by Austria and Germany (N = 195, 30%; N = 79, 12.15% and N = 75, 11.54%, respectively). The majority of cases were in the working-age groups, 18–44 and 45–64 years (56.46% and 34.15%, respectively). Overall, 54 (8.31%) patients developed pneumonia. In comparison to patients without pneumonia, those with pneumonia were older (mean age = 55.39 years vs. 41.34 years, p<0.01) and had a higher percentage of comorbidities (57.41% vs. 16.61%). Men were more likely to develop pneumonia than women (OR = 2.22; 95% CI: 1.14–4.30, p = 0.02), as well as those in retired-age group (OR = 4.11; 95% CI: 2.0–8.46, p<0.01). Obesity (OR = 14.40; 95% CI: 3.8–54.6, p<0.01), diabetes (OR = 9.82; 95% CI: 3.15–30.61, p<0.01) and hypertension (OR = 7.99; 95% CI: 3.98–16.02, p<0.01) were the most prominent main comorbidities as predictors of pneumonia. Our results represent general epidemiological and clinical dynamics of COVID-19 disease in Vojvodina. Also, they provide evidence that the predictors of pneumonia were: increasing age, male sex, having underlying comorbidities, an increasing number of days from the return to laboratory confirmation of COVID-19 (OR = 1.08, 95% CI: 1.03–1.12, p<0.01), as well as an increasing number of days from symptoms onset to diagnosis (OR = 1.14, 95% CI: 1.07–1.21, p<0.01), while anosmia and ageusia were protective factors for developing it (OR = 0.31, 95% CI: 0.12–0.79, p = 0.01).
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spelling pubmed-86999802021-12-24 Epidemiological characteristics of COVID-19 travel-associated cases in Vojvodina, Serbia, during 2020 Pustahija, Tatjana Ristić, Mioljub Medić, Snežana Vuković, Vladimir Štrbac, Mirjana Rajčević, Smiljana Patić, Aleksandra Petrović, Vladimir PLoS One Research Article Coronavirus disease 2019 (COVID-19) is currently the biggest public health problem worldwide. Intensive international travel and tourism have greatly contributed to its rapid global spreading. This study is the first comprehensive analysis of the epidemiological characteristics and clinical outcomes of the travel-associated COVID-19 cases in Vojvodina, Serbia, from March 6 to December 31, 2020 and it concerns permanent residents of Serbia. A cross-sectional study was conducted using data from the dedicated surveillance database of the Institute of Public Health of Vojvodina. Overall, 650 travel-associated COVID-19 cases were recorded in Vojvodina during the observed period, mainly imported from Bosnia and Herzegovina, followed by Austria and Germany (N = 195, 30%; N = 79, 12.15% and N = 75, 11.54%, respectively). The majority of cases were in the working-age groups, 18–44 and 45–64 years (56.46% and 34.15%, respectively). Overall, 54 (8.31%) patients developed pneumonia. In comparison to patients without pneumonia, those with pneumonia were older (mean age = 55.39 years vs. 41.34 years, p<0.01) and had a higher percentage of comorbidities (57.41% vs. 16.61%). Men were more likely to develop pneumonia than women (OR = 2.22; 95% CI: 1.14–4.30, p = 0.02), as well as those in retired-age group (OR = 4.11; 95% CI: 2.0–8.46, p<0.01). Obesity (OR = 14.40; 95% CI: 3.8–54.6, p<0.01), diabetes (OR = 9.82; 95% CI: 3.15–30.61, p<0.01) and hypertension (OR = 7.99; 95% CI: 3.98–16.02, p<0.01) were the most prominent main comorbidities as predictors of pneumonia. Our results represent general epidemiological and clinical dynamics of COVID-19 disease in Vojvodina. Also, they provide evidence that the predictors of pneumonia were: increasing age, male sex, having underlying comorbidities, an increasing number of days from the return to laboratory confirmation of COVID-19 (OR = 1.08, 95% CI: 1.03–1.12, p<0.01), as well as an increasing number of days from symptoms onset to diagnosis (OR = 1.14, 95% CI: 1.07–1.21, p<0.01), while anosmia and ageusia were protective factors for developing it (OR = 0.31, 95% CI: 0.12–0.79, p = 0.01). Public Library of Science 2021-12-23 /pmc/articles/PMC8699980/ /pubmed/34941947 http://dx.doi.org/10.1371/journal.pone.0261840 Text en © 2021 Pustahija et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Pustahija, Tatjana
Ristić, Mioljub
Medić, Snežana
Vuković, Vladimir
Štrbac, Mirjana
Rajčević, Smiljana
Patić, Aleksandra
Petrović, Vladimir
Epidemiological characteristics of COVID-19 travel-associated cases in Vojvodina, Serbia, during 2020
title Epidemiological characteristics of COVID-19 travel-associated cases in Vojvodina, Serbia, during 2020
title_full Epidemiological characteristics of COVID-19 travel-associated cases in Vojvodina, Serbia, during 2020
title_fullStr Epidemiological characteristics of COVID-19 travel-associated cases in Vojvodina, Serbia, during 2020
title_full_unstemmed Epidemiological characteristics of COVID-19 travel-associated cases in Vojvodina, Serbia, during 2020
title_short Epidemiological characteristics of COVID-19 travel-associated cases in Vojvodina, Serbia, during 2020
title_sort epidemiological characteristics of covid-19 travel-associated cases in vojvodina, serbia, during 2020
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699980/
https://www.ncbi.nlm.nih.gov/pubmed/34941947
http://dx.doi.org/10.1371/journal.pone.0261840
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