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Economic evaluation of population-based type 2 diabetes mellitus screening at different healthcare settings in Vietnam

INTRODUCTION: Few economic evaluations have assessed the cost-effectiveness of screening type-2 diabetes mellitus (T2DM) in different healthcare settings. This study aims to evaluate the value for money of various T2DM screening strategies in Vietnam. METHODS: A decision analytical model was constru...

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Autores principales: Toi, Phung Lam, Wu, Olivia, Thavorncharoensap, Montarat, Srinonprasert, Varalak, Anothaisintawee, Thunyarat, Thakkinstian, Ammarin, Phuong, Nguyen Khanh, Chaikledkaew, Usa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700026/
https://www.ncbi.nlm.nih.gov/pubmed/34941883
http://dx.doi.org/10.1371/journal.pone.0261231
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author Toi, Phung Lam
Wu, Olivia
Thavorncharoensap, Montarat
Srinonprasert, Varalak
Anothaisintawee, Thunyarat
Thakkinstian, Ammarin
Phuong, Nguyen Khanh
Chaikledkaew, Usa
author_facet Toi, Phung Lam
Wu, Olivia
Thavorncharoensap, Montarat
Srinonprasert, Varalak
Anothaisintawee, Thunyarat
Thakkinstian, Ammarin
Phuong, Nguyen Khanh
Chaikledkaew, Usa
author_sort Toi, Phung Lam
collection PubMed
description INTRODUCTION: Few economic evaluations have assessed the cost-effectiveness of screening type-2 diabetes mellitus (T2DM) in different healthcare settings. This study aims to evaluate the value for money of various T2DM screening strategies in Vietnam. METHODS: A decision analytical model was constructed to compare costs and quality-adjusted life years (QALYs) of T2DM screening in different health care settings, including (1) screening at commune health station (CHS) and (2) screening at district health center (DHC), with no screening as the current practice. We further explored the costs and QALYs of different initial screening ages and different screening intervals. Cost and utility data were obtained by primary data collection in Vietnam. Incremental cost-effectiveness ratios were calculated from societal and payer perspectives, while uncertainty analysis was performed to explore parameter uncertainties. RESULTS: Annual T2DM screening at either CHS or DHC was cost-effective in Vietnam, from both societal and payer perspectives. Annual screening at CHS was found as the best screening strategy in terms of value for money. From a societal perspective, annual screening at CHS from initial age of 40 years was associated with 0.40 QALYs gained while saving US$ 186.21. Meanwhile, one-off screening was not cost-effective when screening for people younger than 35 years old at both CHS and DHC. CONCLUSIONS: T2DM screening should be included in the Vietnamese health benefits package, and annual screening at either CHS or DHC is recommended.
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spelling pubmed-87000262021-12-24 Economic evaluation of population-based type 2 diabetes mellitus screening at different healthcare settings in Vietnam Toi, Phung Lam Wu, Olivia Thavorncharoensap, Montarat Srinonprasert, Varalak Anothaisintawee, Thunyarat Thakkinstian, Ammarin Phuong, Nguyen Khanh Chaikledkaew, Usa PLoS One Research Article INTRODUCTION: Few economic evaluations have assessed the cost-effectiveness of screening type-2 diabetes mellitus (T2DM) in different healthcare settings. This study aims to evaluate the value for money of various T2DM screening strategies in Vietnam. METHODS: A decision analytical model was constructed to compare costs and quality-adjusted life years (QALYs) of T2DM screening in different health care settings, including (1) screening at commune health station (CHS) and (2) screening at district health center (DHC), with no screening as the current practice. We further explored the costs and QALYs of different initial screening ages and different screening intervals. Cost and utility data were obtained by primary data collection in Vietnam. Incremental cost-effectiveness ratios were calculated from societal and payer perspectives, while uncertainty analysis was performed to explore parameter uncertainties. RESULTS: Annual T2DM screening at either CHS or DHC was cost-effective in Vietnam, from both societal and payer perspectives. Annual screening at CHS was found as the best screening strategy in terms of value for money. From a societal perspective, annual screening at CHS from initial age of 40 years was associated with 0.40 QALYs gained while saving US$ 186.21. Meanwhile, one-off screening was not cost-effective when screening for people younger than 35 years old at both CHS and DHC. CONCLUSIONS: T2DM screening should be included in the Vietnamese health benefits package, and annual screening at either CHS or DHC is recommended. Public Library of Science 2021-12-23 /pmc/articles/PMC8700026/ /pubmed/34941883 http://dx.doi.org/10.1371/journal.pone.0261231 Text en © 2021 Toi et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Toi, Phung Lam
Wu, Olivia
Thavorncharoensap, Montarat
Srinonprasert, Varalak
Anothaisintawee, Thunyarat
Thakkinstian, Ammarin
Phuong, Nguyen Khanh
Chaikledkaew, Usa
Economic evaluation of population-based type 2 diabetes mellitus screening at different healthcare settings in Vietnam
title Economic evaluation of population-based type 2 diabetes mellitus screening at different healthcare settings in Vietnam
title_full Economic evaluation of population-based type 2 diabetes mellitus screening at different healthcare settings in Vietnam
title_fullStr Economic evaluation of population-based type 2 diabetes mellitus screening at different healthcare settings in Vietnam
title_full_unstemmed Economic evaluation of population-based type 2 diabetes mellitus screening at different healthcare settings in Vietnam
title_short Economic evaluation of population-based type 2 diabetes mellitus screening at different healthcare settings in Vietnam
title_sort economic evaluation of population-based type 2 diabetes mellitus screening at different healthcare settings in vietnam
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700026/
https://www.ncbi.nlm.nih.gov/pubmed/34941883
http://dx.doi.org/10.1371/journal.pone.0261231
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