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Pulmonary Vasculitides: A Radiological Review Emphasizing Parenchymal HRCT Features

Vasculitides represent a heterogeneous group of immune-mediated disorders, characterized by a systemic inflammatory destructive process of the blood vessels resulting either in ischemia or hemorrhage. The organ involved and vessel size influence the pattern of presentation of the pathology. The lung...

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Autores principales: Palmucci, Stefano, Inì, Corrado, Cosentino, Salvatore, Fanzone, Luigi, Di Pietro, Stefano, Di Mari, Alessia, Galioto, Federica, Tiralongo, Francesco, Vignigni, Giovanna, Toscano, Stefano, Sambataro, Gianluca, Vancheri, Carlo, Distefano, Giulio, Basile, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700038/
https://www.ncbi.nlm.nih.gov/pubmed/34943555
http://dx.doi.org/10.3390/diagnostics11122318
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author Palmucci, Stefano
Inì, Corrado
Cosentino, Salvatore
Fanzone, Luigi
Di Pietro, Stefano
Di Mari, Alessia
Galioto, Federica
Tiralongo, Francesco
Vignigni, Giovanna
Toscano, Stefano
Sambataro, Gianluca
Vancheri, Carlo
Distefano, Giulio
Basile, Antonio
author_facet Palmucci, Stefano
Inì, Corrado
Cosentino, Salvatore
Fanzone, Luigi
Di Pietro, Stefano
Di Mari, Alessia
Galioto, Federica
Tiralongo, Francesco
Vignigni, Giovanna
Toscano, Stefano
Sambataro, Gianluca
Vancheri, Carlo
Distefano, Giulio
Basile, Antonio
author_sort Palmucci, Stefano
collection PubMed
description Vasculitides represent a heterogeneous group of immune-mediated disorders, characterized by a systemic inflammatory destructive process of the blood vessels resulting either in ischemia or hemorrhage. The organ involved and vessel size influence the pattern of presentation of the pathology. The lung is commonly involved in systemic vasculitides, with heterogeneous clinical, radiological, and histopathological presentations. Primary vasculitides most commonly associated with lung parenchymal involvement include small-vessel antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitides, such as granulomatosis with polyangiitis (GPA), eosinophilic granulomatosis with polyangiitis (EGPA), and microscopic polyangiitis (MPA). Several studies have reported cases of interstitial lung diseases (ILDs) associated with systemic vasculitis, particularly those positive for ANCA associated vasculitis/vasculitidis: AAV. We have selected from our case series different radiological features of pulmonary vasculitis (i.e., solitary or multiple nodules, cavitary lesions, nodules with centrilobular or peribronchial distribution, airspace consolidations, “crazy paving” appearance, interstitial disease), including cases with interstitial lung alterations. Therefore, the aim of this review is to describe the typical clinical manifestations of vasculitides and their main radiologic features (especially AAV).
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spelling pubmed-87000382021-12-24 Pulmonary Vasculitides: A Radiological Review Emphasizing Parenchymal HRCT Features Palmucci, Stefano Inì, Corrado Cosentino, Salvatore Fanzone, Luigi Di Pietro, Stefano Di Mari, Alessia Galioto, Federica Tiralongo, Francesco Vignigni, Giovanna Toscano, Stefano Sambataro, Gianluca Vancheri, Carlo Distefano, Giulio Basile, Antonio Diagnostics (Basel) Review Vasculitides represent a heterogeneous group of immune-mediated disorders, characterized by a systemic inflammatory destructive process of the blood vessels resulting either in ischemia or hemorrhage. The organ involved and vessel size influence the pattern of presentation of the pathology. The lung is commonly involved in systemic vasculitides, with heterogeneous clinical, radiological, and histopathological presentations. Primary vasculitides most commonly associated with lung parenchymal involvement include small-vessel antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitides, such as granulomatosis with polyangiitis (GPA), eosinophilic granulomatosis with polyangiitis (EGPA), and microscopic polyangiitis (MPA). Several studies have reported cases of interstitial lung diseases (ILDs) associated with systemic vasculitis, particularly those positive for ANCA associated vasculitis/vasculitidis: AAV. We have selected from our case series different radiological features of pulmonary vasculitis (i.e., solitary or multiple nodules, cavitary lesions, nodules with centrilobular or peribronchial distribution, airspace consolidations, “crazy paving” appearance, interstitial disease), including cases with interstitial lung alterations. Therefore, the aim of this review is to describe the typical clinical manifestations of vasculitides and their main radiologic features (especially AAV). MDPI 2021-12-09 /pmc/articles/PMC8700038/ /pubmed/34943555 http://dx.doi.org/10.3390/diagnostics11122318 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Palmucci, Stefano
Inì, Corrado
Cosentino, Salvatore
Fanzone, Luigi
Di Pietro, Stefano
Di Mari, Alessia
Galioto, Federica
Tiralongo, Francesco
Vignigni, Giovanna
Toscano, Stefano
Sambataro, Gianluca
Vancheri, Carlo
Distefano, Giulio
Basile, Antonio
Pulmonary Vasculitides: A Radiological Review Emphasizing Parenchymal HRCT Features
title Pulmonary Vasculitides: A Radiological Review Emphasizing Parenchymal HRCT Features
title_full Pulmonary Vasculitides: A Radiological Review Emphasizing Parenchymal HRCT Features
title_fullStr Pulmonary Vasculitides: A Radiological Review Emphasizing Parenchymal HRCT Features
title_full_unstemmed Pulmonary Vasculitides: A Radiological Review Emphasizing Parenchymal HRCT Features
title_short Pulmonary Vasculitides: A Radiological Review Emphasizing Parenchymal HRCT Features
title_sort pulmonary vasculitides: a radiological review emphasizing parenchymal hrct features
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700038/
https://www.ncbi.nlm.nih.gov/pubmed/34943555
http://dx.doi.org/10.3390/diagnostics11122318
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