Cargando…
Pulmonary Vasculitides: A Radiological Review Emphasizing Parenchymal HRCT Features
Vasculitides represent a heterogeneous group of immune-mediated disorders, characterized by a systemic inflammatory destructive process of the blood vessels resulting either in ischemia or hemorrhage. The organ involved and vessel size influence the pattern of presentation of the pathology. The lung...
Autores principales: | , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700038/ https://www.ncbi.nlm.nih.gov/pubmed/34943555 http://dx.doi.org/10.3390/diagnostics11122318 |
_version_ | 1784620659609960448 |
---|---|
author | Palmucci, Stefano Inì, Corrado Cosentino, Salvatore Fanzone, Luigi Di Pietro, Stefano Di Mari, Alessia Galioto, Federica Tiralongo, Francesco Vignigni, Giovanna Toscano, Stefano Sambataro, Gianluca Vancheri, Carlo Distefano, Giulio Basile, Antonio |
author_facet | Palmucci, Stefano Inì, Corrado Cosentino, Salvatore Fanzone, Luigi Di Pietro, Stefano Di Mari, Alessia Galioto, Federica Tiralongo, Francesco Vignigni, Giovanna Toscano, Stefano Sambataro, Gianluca Vancheri, Carlo Distefano, Giulio Basile, Antonio |
author_sort | Palmucci, Stefano |
collection | PubMed |
description | Vasculitides represent a heterogeneous group of immune-mediated disorders, characterized by a systemic inflammatory destructive process of the blood vessels resulting either in ischemia or hemorrhage. The organ involved and vessel size influence the pattern of presentation of the pathology. The lung is commonly involved in systemic vasculitides, with heterogeneous clinical, radiological, and histopathological presentations. Primary vasculitides most commonly associated with lung parenchymal involvement include small-vessel antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitides, such as granulomatosis with polyangiitis (GPA), eosinophilic granulomatosis with polyangiitis (EGPA), and microscopic polyangiitis (MPA). Several studies have reported cases of interstitial lung diseases (ILDs) associated with systemic vasculitis, particularly those positive for ANCA associated vasculitis/vasculitidis: AAV. We have selected from our case series different radiological features of pulmonary vasculitis (i.e., solitary or multiple nodules, cavitary lesions, nodules with centrilobular or peribronchial distribution, airspace consolidations, “crazy paving” appearance, interstitial disease), including cases with interstitial lung alterations. Therefore, the aim of this review is to describe the typical clinical manifestations of vasculitides and their main radiologic features (especially AAV). |
format | Online Article Text |
id | pubmed-8700038 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87000382021-12-24 Pulmonary Vasculitides: A Radiological Review Emphasizing Parenchymal HRCT Features Palmucci, Stefano Inì, Corrado Cosentino, Salvatore Fanzone, Luigi Di Pietro, Stefano Di Mari, Alessia Galioto, Federica Tiralongo, Francesco Vignigni, Giovanna Toscano, Stefano Sambataro, Gianluca Vancheri, Carlo Distefano, Giulio Basile, Antonio Diagnostics (Basel) Review Vasculitides represent a heterogeneous group of immune-mediated disorders, characterized by a systemic inflammatory destructive process of the blood vessels resulting either in ischemia or hemorrhage. The organ involved and vessel size influence the pattern of presentation of the pathology. The lung is commonly involved in systemic vasculitides, with heterogeneous clinical, radiological, and histopathological presentations. Primary vasculitides most commonly associated with lung parenchymal involvement include small-vessel antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitides, such as granulomatosis with polyangiitis (GPA), eosinophilic granulomatosis with polyangiitis (EGPA), and microscopic polyangiitis (MPA). Several studies have reported cases of interstitial lung diseases (ILDs) associated with systemic vasculitis, particularly those positive for ANCA associated vasculitis/vasculitidis: AAV. We have selected from our case series different radiological features of pulmonary vasculitis (i.e., solitary or multiple nodules, cavitary lesions, nodules with centrilobular or peribronchial distribution, airspace consolidations, “crazy paving” appearance, interstitial disease), including cases with interstitial lung alterations. Therefore, the aim of this review is to describe the typical clinical manifestations of vasculitides and their main radiologic features (especially AAV). MDPI 2021-12-09 /pmc/articles/PMC8700038/ /pubmed/34943555 http://dx.doi.org/10.3390/diagnostics11122318 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Palmucci, Stefano Inì, Corrado Cosentino, Salvatore Fanzone, Luigi Di Pietro, Stefano Di Mari, Alessia Galioto, Federica Tiralongo, Francesco Vignigni, Giovanna Toscano, Stefano Sambataro, Gianluca Vancheri, Carlo Distefano, Giulio Basile, Antonio Pulmonary Vasculitides: A Radiological Review Emphasizing Parenchymal HRCT Features |
title | Pulmonary Vasculitides: A Radiological Review Emphasizing Parenchymal HRCT Features |
title_full | Pulmonary Vasculitides: A Radiological Review Emphasizing Parenchymal HRCT Features |
title_fullStr | Pulmonary Vasculitides: A Radiological Review Emphasizing Parenchymal HRCT Features |
title_full_unstemmed | Pulmonary Vasculitides: A Radiological Review Emphasizing Parenchymal HRCT Features |
title_short | Pulmonary Vasculitides: A Radiological Review Emphasizing Parenchymal HRCT Features |
title_sort | pulmonary vasculitides: a radiological review emphasizing parenchymal hrct features |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700038/ https://www.ncbi.nlm.nih.gov/pubmed/34943555 http://dx.doi.org/10.3390/diagnostics11122318 |
work_keys_str_mv | AT palmuccistefano pulmonaryvasculitidesaradiologicalreviewemphasizingparenchymalhrctfeatures AT inicorrado pulmonaryvasculitidesaradiologicalreviewemphasizingparenchymalhrctfeatures AT cosentinosalvatore pulmonaryvasculitidesaradiologicalreviewemphasizingparenchymalhrctfeatures AT fanzoneluigi pulmonaryvasculitidesaradiologicalreviewemphasizingparenchymalhrctfeatures AT dipietrostefano pulmonaryvasculitidesaradiologicalreviewemphasizingparenchymalhrctfeatures AT dimarialessia pulmonaryvasculitidesaradiologicalreviewemphasizingparenchymalhrctfeatures AT galiotofederica pulmonaryvasculitidesaradiologicalreviewemphasizingparenchymalhrctfeatures AT tiralongofrancesco pulmonaryvasculitidesaradiologicalreviewemphasizingparenchymalhrctfeatures AT vignignigiovanna pulmonaryvasculitidesaradiologicalreviewemphasizingparenchymalhrctfeatures AT toscanostefano pulmonaryvasculitidesaradiologicalreviewemphasizingparenchymalhrctfeatures AT sambatarogianluca pulmonaryvasculitidesaradiologicalreviewemphasizingparenchymalhrctfeatures AT vanchericarlo pulmonaryvasculitidesaradiologicalreviewemphasizingparenchymalhrctfeatures AT distefanogiulio pulmonaryvasculitidesaradiologicalreviewemphasizingparenchymalhrctfeatures AT basileantonio pulmonaryvasculitidesaradiologicalreviewemphasizingparenchymalhrctfeatures |