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Fibroblast Growth Factor 21 (FGF21) Administration Sex-Specifically Affects Blood Insulin Levels and Liver Steatosis in Obese A(y) Mice

FGF21 is a promising candidate for treating obesity, diabetes, and NAFLD; however, some of its pharmacological effects are sex-specific in mice with the A(y) mutation that evokes melanocortin receptor 4 blockade, obesity, and hepatosteatosis. This suggests that the ability of FGF21 to correct melano...

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Detalles Bibliográficos
Autores principales: Makarova, Elena, Kazantseva, Antonina, Dubinina, Anastasia, Denisova, Elena, Jakovleva, Tatiana, Balybina, Natalia, Bgatova, Nataliya, Baranov, Konstantin, Bazhan, Nadezhda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700098/
https://www.ncbi.nlm.nih.gov/pubmed/34943946
http://dx.doi.org/10.3390/cells10123440