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Fibroblast Growth Factor 21 (FGF21) Administration Sex-Specifically Affects Blood Insulin Levels and Liver Steatosis in Obese A(y) Mice
FGF21 is a promising candidate for treating obesity, diabetes, and NAFLD; however, some of its pharmacological effects are sex-specific in mice with the A(y) mutation that evokes melanocortin receptor 4 blockade, obesity, and hepatosteatosis. This suggests that the ability of FGF21 to correct melano...
Autores principales: | Makarova, Elena, Kazantseva, Antonina, Dubinina, Anastasia, Denisova, Elena, Jakovleva, Tatiana, Balybina, Natalia, Bgatova, Nataliya, Baranov, Konstantin, Bazhan, Nadezhda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700098/ https://www.ncbi.nlm.nih.gov/pubmed/34943946 http://dx.doi.org/10.3390/cells10123440 |
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