Cargando…
Maternal Perinatal Depression and Risk of Neurodevelopmental Disorders in Offspring: Preliminary Results from the SOS MOOD Project
The latest research is attempting to define whether there may be an association between maternal Perinatal Depression (PD), the use of psychotropic medications during pregnancy, and a higher risk of neurodevelopmental disorders in children, including Autism Spectrum Disorder (ASD). A better understa...
Autores principales: | , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700100/ https://www.ncbi.nlm.nih.gov/pubmed/34943347 http://dx.doi.org/10.3390/children8121150 |
_version_ | 1784620675021930496 |
---|---|
author | Siracusano, Martina Riccioni, Assia Gialloreti, Leonardo Emberti Carloni, Elisa Baratta, Antonia Ferrara, Marialaura Arturi, Lucrezia Lisi, Giulia Adulti, Ilaria Rossi, Rodolfo Lucaselli, Alessia Rossi, Alessandro Niolu, Cinzia Mazzone, Luigi |
author_facet | Siracusano, Martina Riccioni, Assia Gialloreti, Leonardo Emberti Carloni, Elisa Baratta, Antonia Ferrara, Marialaura Arturi, Lucrezia Lisi, Giulia Adulti, Ilaria Rossi, Rodolfo Lucaselli, Alessia Rossi, Alessandro Niolu, Cinzia Mazzone, Luigi |
author_sort | Siracusano, Martina |
collection | PubMed |
description | The latest research is attempting to define whether there may be an association between maternal Perinatal Depression (PD), the use of psychotropic medications during pregnancy, and a higher risk of neurodevelopmental disorders in children, including Autism Spectrum Disorder (ASD). A better understanding of the relation between PD and ASD is a key element to develop early interventions. This study has been developed in the context of the SOS MOOD project. Its aim is to evaluate the possible impact of maternal PD on the child’s cognitive and behavioral phenotype with a focus on ASD. Women included in the project were screened during pregnancy (1st, 2nd trimester) for PD—categorized as affected or not—and if necessary were prescribed pharmacological therapy; offspring of both groups of women underwent at a mean age of 43 months a standardized neuropsychiatric evaluation of developmental and cognitive skills, behavioral problems, autism symptoms and parental stress. Preliminary results on 59 women and 59 children do not suggest significant long-term effects of maternal PD on offspring’s development and behavior. Nonetheless further studies on wider samples are necessary in order to confirm such results and disentangle the role of possible confounding factors associated to the maternal illness. |
format | Online Article Text |
id | pubmed-8700100 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87001002021-12-24 Maternal Perinatal Depression and Risk of Neurodevelopmental Disorders in Offspring: Preliminary Results from the SOS MOOD Project Siracusano, Martina Riccioni, Assia Gialloreti, Leonardo Emberti Carloni, Elisa Baratta, Antonia Ferrara, Marialaura Arturi, Lucrezia Lisi, Giulia Adulti, Ilaria Rossi, Rodolfo Lucaselli, Alessia Rossi, Alessandro Niolu, Cinzia Mazzone, Luigi Children (Basel) Article The latest research is attempting to define whether there may be an association between maternal Perinatal Depression (PD), the use of psychotropic medications during pregnancy, and a higher risk of neurodevelopmental disorders in children, including Autism Spectrum Disorder (ASD). A better understanding of the relation between PD and ASD is a key element to develop early interventions. This study has been developed in the context of the SOS MOOD project. Its aim is to evaluate the possible impact of maternal PD on the child’s cognitive and behavioral phenotype with a focus on ASD. Women included in the project were screened during pregnancy (1st, 2nd trimester) for PD—categorized as affected or not—and if necessary were prescribed pharmacological therapy; offspring of both groups of women underwent at a mean age of 43 months a standardized neuropsychiatric evaluation of developmental and cognitive skills, behavioral problems, autism symptoms and parental stress. Preliminary results on 59 women and 59 children do not suggest significant long-term effects of maternal PD on offspring’s development and behavior. Nonetheless further studies on wider samples are necessary in order to confirm such results and disentangle the role of possible confounding factors associated to the maternal illness. MDPI 2021-12-07 /pmc/articles/PMC8700100/ /pubmed/34943347 http://dx.doi.org/10.3390/children8121150 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Siracusano, Martina Riccioni, Assia Gialloreti, Leonardo Emberti Carloni, Elisa Baratta, Antonia Ferrara, Marialaura Arturi, Lucrezia Lisi, Giulia Adulti, Ilaria Rossi, Rodolfo Lucaselli, Alessia Rossi, Alessandro Niolu, Cinzia Mazzone, Luigi Maternal Perinatal Depression and Risk of Neurodevelopmental Disorders in Offspring: Preliminary Results from the SOS MOOD Project |
title | Maternal Perinatal Depression and Risk of Neurodevelopmental Disorders in Offspring: Preliminary Results from the SOS MOOD Project |
title_full | Maternal Perinatal Depression and Risk of Neurodevelopmental Disorders in Offspring: Preliminary Results from the SOS MOOD Project |
title_fullStr | Maternal Perinatal Depression and Risk of Neurodevelopmental Disorders in Offspring: Preliminary Results from the SOS MOOD Project |
title_full_unstemmed | Maternal Perinatal Depression and Risk of Neurodevelopmental Disorders in Offspring: Preliminary Results from the SOS MOOD Project |
title_short | Maternal Perinatal Depression and Risk of Neurodevelopmental Disorders in Offspring: Preliminary Results from the SOS MOOD Project |
title_sort | maternal perinatal depression and risk of neurodevelopmental disorders in offspring: preliminary results from the sos mood project |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700100/ https://www.ncbi.nlm.nih.gov/pubmed/34943347 http://dx.doi.org/10.3390/children8121150 |
work_keys_str_mv | AT siracusanomartina maternalperinataldepressionandriskofneurodevelopmentaldisordersinoffspringpreliminaryresultsfromthesosmoodproject AT riccioniassia maternalperinataldepressionandriskofneurodevelopmentaldisordersinoffspringpreliminaryresultsfromthesosmoodproject AT gialloretileonardoemberti maternalperinataldepressionandriskofneurodevelopmentaldisordersinoffspringpreliminaryresultsfromthesosmoodproject AT carlonielisa maternalperinataldepressionandriskofneurodevelopmentaldisordersinoffspringpreliminaryresultsfromthesosmoodproject AT barattaantonia maternalperinataldepressionandriskofneurodevelopmentaldisordersinoffspringpreliminaryresultsfromthesosmoodproject AT ferraramarialaura maternalperinataldepressionandriskofneurodevelopmentaldisordersinoffspringpreliminaryresultsfromthesosmoodproject AT arturilucrezia maternalperinataldepressionandriskofneurodevelopmentaldisordersinoffspringpreliminaryresultsfromthesosmoodproject AT lisigiulia maternalperinataldepressionandriskofneurodevelopmentaldisordersinoffspringpreliminaryresultsfromthesosmoodproject AT adultiilaria maternalperinataldepressionandriskofneurodevelopmentaldisordersinoffspringpreliminaryresultsfromthesosmoodproject AT rossirodolfo maternalperinataldepressionandriskofneurodevelopmentaldisordersinoffspringpreliminaryresultsfromthesosmoodproject AT lucasellialessia maternalperinataldepressionandriskofneurodevelopmentaldisordersinoffspringpreliminaryresultsfromthesosmoodproject AT rossialessandro maternalperinataldepressionandriskofneurodevelopmentaldisordersinoffspringpreliminaryresultsfromthesosmoodproject AT niolucinzia maternalperinataldepressionandriskofneurodevelopmentaldisordersinoffspringpreliminaryresultsfromthesosmoodproject AT mazzoneluigi maternalperinataldepressionandriskofneurodevelopmentaldisordersinoffspringpreliminaryresultsfromthesosmoodproject |