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Repeated Low-Dose Acrolein Triggers Irreversible Lamina Propria Edema in Urinary Bladder, Transient Voiding Behavior and Widening of Eyes to Mechanical Stimuli

Acrolein is a metabolite of cyclophosphamide (CYP), an alkylating agent used for a wide range of benign and malignant diseases. CYP treatments are known to trigger hemorrhagic cystitis in patients and animals. Significant effort has been made to prevent CYP/acrolein-induced cystitis, while still mai...

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Detalles Bibliográficos
Autores principales: Lee, Sanghee, Lee, Jiwoo, Khimji, Chandresh, Lee, Jaebeom, Malkmus, Shelle, Albo, Michael, Yaksh, Tony, Chiang, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700116/
https://www.ncbi.nlm.nih.gov/pubmed/34943985
http://dx.doi.org/10.3390/cells10123477