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Repeated Low-Dose Acrolein Triggers Irreversible Lamina Propria Edema in Urinary Bladder, Transient Voiding Behavior and Widening of Eyes to Mechanical Stimuli
Acrolein is a metabolite of cyclophosphamide (CYP), an alkylating agent used for a wide range of benign and malignant diseases. CYP treatments are known to trigger hemorrhagic cystitis in patients and animals. Significant effort has been made to prevent CYP/acrolein-induced cystitis, while still mai...
Autores principales: | Lee, Sanghee, Lee, Jiwoo, Khimji, Chandresh, Lee, Jaebeom, Malkmus, Shelle, Albo, Michael, Yaksh, Tony, Chiang, George |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700116/ https://www.ncbi.nlm.nih.gov/pubmed/34943985 http://dx.doi.org/10.3390/cells10123477 |
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