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Exploring the Binding Pattern of Geraniol with Acetylcholinesterase through In Silico Docking, Molecular Dynamics Simulation, and In Vitro Enzyme Inhibition Kinetics Studies

Acetylcholinesterase (AChE) inhibition is a key element in enhancing cholinergic transmission and subsequently relieving major symptoms of several neurological and neuromuscular disorders. Here, the inhibitory potential of geraniol and its mechanism of inhibition against AChE were elucidated in vitr...

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Detalles Bibliográficos
Autores principales:	Iqbal, Danish, Khan, M. Salman, Waiz, Mohd, Rehman, Md Tabish, Alaidarous, Mohammed, Jamal, Azfar, Alothaim, Abdulaziz S., AlAjmi, Mohamed F, Alshehri, Bader Mohammed, Banawas, Saeed, Alsaweed, Mohammed, Madkhali, Yahya, Algarni, Abdulrahman, Alsagaby, Suliman A., Alturaiki, Wael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700130/ https://www.ncbi.nlm.nih.gov/pubmed/34944045 http://dx.doi.org/10.3390/cells10123533

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