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Extracellular Signalling Modulates Scar/WAVE Complex Activity through Abi Phosphorylation

The lamellipodia and pseudopodia of migrating cells are produced and maintained by the Scar/WAVE complex. Thus, actin-based cell migration is largely controlled through regulation of Scar/WAVE. Here, we report that the Abi subunit—but not Scar—is phosphorylated in response to extracellular signallin...

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Detalles Bibliográficos
Autores principales: Singh, Shashi Prakash, Thomason, Peter A., Insall, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700165/
https://www.ncbi.nlm.nih.gov/pubmed/34943993
http://dx.doi.org/10.3390/cells10123485