Cargando…

Opportunistic Colonoscopy Cancer Screening Pays off in Romania—A Single-Centre Study

Colorectal cancer (CRC) is the third most diagnosed cancer in men (after prostate and lung cancers) and in women (after breast and lung cancer). It is the second cause of cancer death in men (after lung cancer) and the third one in women (after breast and lung cancers). It is estimated that, in EU-2...

Descripción completa

Detalles Bibliográficos
Autores principales: Rațiu, Iulia, Lupușoru, Raluca, Vora, Prateek, Popescu, Alina, Sporea, Ioan, Goldiș, Adrian, Dănilă, Mirela, Miuțescu, Bogdan, Barbulescu, Andreea, Hnatiuc, Madalina, Diaconescu, Razvan, Tăban, Sorina, Lazar, Fulger, Șirli, Roxana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700238/
https://www.ncbi.nlm.nih.gov/pubmed/34943629
http://dx.doi.org/10.3390/diagnostics11122393
_version_ 1784620708826972160
author Rațiu, Iulia
Lupușoru, Raluca
Vora, Prateek
Popescu, Alina
Sporea, Ioan
Goldiș, Adrian
Dănilă, Mirela
Miuțescu, Bogdan
Barbulescu, Andreea
Hnatiuc, Madalina
Diaconescu, Razvan
Tăban, Sorina
Lazar, Fulger
Șirli, Roxana
author_facet Rațiu, Iulia
Lupușoru, Raluca
Vora, Prateek
Popescu, Alina
Sporea, Ioan
Goldiș, Adrian
Dănilă, Mirela
Miuțescu, Bogdan
Barbulescu, Andreea
Hnatiuc, Madalina
Diaconescu, Razvan
Tăban, Sorina
Lazar, Fulger
Șirli, Roxana
author_sort Rațiu, Iulia
collection PubMed
description Colorectal cancer (CRC) is the third most diagnosed cancer in men (after prostate and lung cancers) and in women (after breast and lung cancer). It is the second cause of cancer death in men (after lung cancer) and the third one in women (after breast and lung cancers). It is estimated that, in EU-27 countries in 2020, colorectal cancer accounted for 12.7% of all new cancer diagnoses and 12.4% of all deaths due to cancer. Our study aims to assess the opportunistic colorectal cancer screening by colonoscopy in a private hospital. A secondary objective of this study is to analyse the adenoma detection rate (ADR), polyp detection rate (PDR), and colorectal cancer (CRC) detection rate. We designed a retrospective single-centre study in the Gastroenterology Department of Saint Mary Hospital. The study population includes all individuals who performed colonoscopies in 2 years, January 2019–December 2020, addressed to our department by their family physician or came by themselves for a colonoscopy. One thousand seven hundred seventy-eight asymptomatic subjects underwent a colonoscopy for the first time. The mean age was 59.0 ± 10.9, 59.5% female. Eight hundred seventy-three polyps were found in 525 patients. Five hundred and twenty-five had at least one polyp, 185 patients had two polyps, 87 had three polyps, and 40 patients had more than three polyps. The PDR was 49.1%, ADR 39.0%, advanced adenomas in 7.9%, and carcinomas were found in 5.4% of patients. In a country without any colorectal cancer screening policy, polyps were found in almost half of the 1778 asymptomatic patients evaluated in a single private center, 39% of cases adenomas, and 5.4% colorectal cancer. Our study suggests starting screening colonoscopy at the age of 45. A poor bowel preparation significantly impacted the adenoma detection rate.
format Online
Article
Text
id pubmed-8700238
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-87002382021-12-24 Opportunistic Colonoscopy Cancer Screening Pays off in Romania—A Single-Centre Study Rațiu, Iulia Lupușoru, Raluca Vora, Prateek Popescu, Alina Sporea, Ioan Goldiș, Adrian Dănilă, Mirela Miuțescu, Bogdan Barbulescu, Andreea Hnatiuc, Madalina Diaconescu, Razvan Tăban, Sorina Lazar, Fulger Șirli, Roxana Diagnostics (Basel) Article Colorectal cancer (CRC) is the third most diagnosed cancer in men (after prostate and lung cancers) and in women (after breast and lung cancer). It is the second cause of cancer death in men (after lung cancer) and the third one in women (after breast and lung cancers). It is estimated that, in EU-27 countries in 2020, colorectal cancer accounted for 12.7% of all new cancer diagnoses and 12.4% of all deaths due to cancer. Our study aims to assess the opportunistic colorectal cancer screening by colonoscopy in a private hospital. A secondary objective of this study is to analyse the adenoma detection rate (ADR), polyp detection rate (PDR), and colorectal cancer (CRC) detection rate. We designed a retrospective single-centre study in the Gastroenterology Department of Saint Mary Hospital. The study population includes all individuals who performed colonoscopies in 2 years, January 2019–December 2020, addressed to our department by their family physician or came by themselves for a colonoscopy. One thousand seven hundred seventy-eight asymptomatic subjects underwent a colonoscopy for the first time. The mean age was 59.0 ± 10.9, 59.5% female. Eight hundred seventy-three polyps were found in 525 patients. Five hundred and twenty-five had at least one polyp, 185 patients had two polyps, 87 had three polyps, and 40 patients had more than three polyps. The PDR was 49.1%, ADR 39.0%, advanced adenomas in 7.9%, and carcinomas were found in 5.4% of patients. In a country without any colorectal cancer screening policy, polyps were found in almost half of the 1778 asymptomatic patients evaluated in a single private center, 39% of cases adenomas, and 5.4% colorectal cancer. Our study suggests starting screening colonoscopy at the age of 45. A poor bowel preparation significantly impacted the adenoma detection rate. MDPI 2021-12-19 /pmc/articles/PMC8700238/ /pubmed/34943629 http://dx.doi.org/10.3390/diagnostics11122393 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Rațiu, Iulia
Lupușoru, Raluca
Vora, Prateek
Popescu, Alina
Sporea, Ioan
Goldiș, Adrian
Dănilă, Mirela
Miuțescu, Bogdan
Barbulescu, Andreea
Hnatiuc, Madalina
Diaconescu, Razvan
Tăban, Sorina
Lazar, Fulger
Șirli, Roxana
Opportunistic Colonoscopy Cancer Screening Pays off in Romania—A Single-Centre Study
title Opportunistic Colonoscopy Cancer Screening Pays off in Romania—A Single-Centre Study
title_full Opportunistic Colonoscopy Cancer Screening Pays off in Romania—A Single-Centre Study
title_fullStr Opportunistic Colonoscopy Cancer Screening Pays off in Romania—A Single-Centre Study
title_full_unstemmed Opportunistic Colonoscopy Cancer Screening Pays off in Romania—A Single-Centre Study
title_short Opportunistic Colonoscopy Cancer Screening Pays off in Romania—A Single-Centre Study
title_sort opportunistic colonoscopy cancer screening pays off in romania—a single-centre study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700238/
https://www.ncbi.nlm.nih.gov/pubmed/34943629
http://dx.doi.org/10.3390/diagnostics11122393
work_keys_str_mv AT ratiuiulia opportunisticcolonoscopycancerscreeningpaysoffinromaniaasinglecentrestudy
AT lupusoruraluca opportunisticcolonoscopycancerscreeningpaysoffinromaniaasinglecentrestudy
AT voraprateek opportunisticcolonoscopycancerscreeningpaysoffinromaniaasinglecentrestudy
AT popescualina opportunisticcolonoscopycancerscreeningpaysoffinromaniaasinglecentrestudy
AT sporeaioan opportunisticcolonoscopycancerscreeningpaysoffinromaniaasinglecentrestudy
AT goldisadrian opportunisticcolonoscopycancerscreeningpaysoffinromaniaasinglecentrestudy
AT danilamirela opportunisticcolonoscopycancerscreeningpaysoffinromaniaasinglecentrestudy
AT miutescubogdan opportunisticcolonoscopycancerscreeningpaysoffinromaniaasinglecentrestudy
AT barbulescuandreea opportunisticcolonoscopycancerscreeningpaysoffinromaniaasinglecentrestudy
AT hnatiucmadalina opportunisticcolonoscopycancerscreeningpaysoffinromaniaasinglecentrestudy
AT diaconescurazvan opportunisticcolonoscopycancerscreeningpaysoffinromaniaasinglecentrestudy
AT tabansorina opportunisticcolonoscopycancerscreeningpaysoffinromaniaasinglecentrestudy
AT lazarfulger opportunisticcolonoscopycancerscreeningpaysoffinromaniaasinglecentrestudy
AT sirliroxana opportunisticcolonoscopycancerscreeningpaysoffinromaniaasinglecentrestudy