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Opportunistic Colonoscopy Cancer Screening Pays off in Romania—A Single-Centre Study
Colorectal cancer (CRC) is the third most diagnosed cancer in men (after prostate and lung cancers) and in women (after breast and lung cancer). It is the second cause of cancer death in men (after lung cancer) and the third one in women (after breast and lung cancers). It is estimated that, in EU-2...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700238/ https://www.ncbi.nlm.nih.gov/pubmed/34943629 http://dx.doi.org/10.3390/diagnostics11122393 |
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author | Rațiu, Iulia Lupușoru, Raluca Vora, Prateek Popescu, Alina Sporea, Ioan Goldiș, Adrian Dănilă, Mirela Miuțescu, Bogdan Barbulescu, Andreea Hnatiuc, Madalina Diaconescu, Razvan Tăban, Sorina Lazar, Fulger Șirli, Roxana |
author_facet | Rațiu, Iulia Lupușoru, Raluca Vora, Prateek Popescu, Alina Sporea, Ioan Goldiș, Adrian Dănilă, Mirela Miuțescu, Bogdan Barbulescu, Andreea Hnatiuc, Madalina Diaconescu, Razvan Tăban, Sorina Lazar, Fulger Șirli, Roxana |
author_sort | Rațiu, Iulia |
collection | PubMed |
description | Colorectal cancer (CRC) is the third most diagnosed cancer in men (after prostate and lung cancers) and in women (after breast and lung cancer). It is the second cause of cancer death in men (after lung cancer) and the third one in women (after breast and lung cancers). It is estimated that, in EU-27 countries in 2020, colorectal cancer accounted for 12.7% of all new cancer diagnoses and 12.4% of all deaths due to cancer. Our study aims to assess the opportunistic colorectal cancer screening by colonoscopy in a private hospital. A secondary objective of this study is to analyse the adenoma detection rate (ADR), polyp detection rate (PDR), and colorectal cancer (CRC) detection rate. We designed a retrospective single-centre study in the Gastroenterology Department of Saint Mary Hospital. The study population includes all individuals who performed colonoscopies in 2 years, January 2019–December 2020, addressed to our department by their family physician or came by themselves for a colonoscopy. One thousand seven hundred seventy-eight asymptomatic subjects underwent a colonoscopy for the first time. The mean age was 59.0 ± 10.9, 59.5% female. Eight hundred seventy-three polyps were found in 525 patients. Five hundred and twenty-five had at least one polyp, 185 patients had two polyps, 87 had three polyps, and 40 patients had more than three polyps. The PDR was 49.1%, ADR 39.0%, advanced adenomas in 7.9%, and carcinomas were found in 5.4% of patients. In a country without any colorectal cancer screening policy, polyps were found in almost half of the 1778 asymptomatic patients evaluated in a single private center, 39% of cases adenomas, and 5.4% colorectal cancer. Our study suggests starting screening colonoscopy at the age of 45. A poor bowel preparation significantly impacted the adenoma detection rate. |
format | Online Article Text |
id | pubmed-8700238 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87002382021-12-24 Opportunistic Colonoscopy Cancer Screening Pays off in Romania—A Single-Centre Study Rațiu, Iulia Lupușoru, Raluca Vora, Prateek Popescu, Alina Sporea, Ioan Goldiș, Adrian Dănilă, Mirela Miuțescu, Bogdan Barbulescu, Andreea Hnatiuc, Madalina Diaconescu, Razvan Tăban, Sorina Lazar, Fulger Șirli, Roxana Diagnostics (Basel) Article Colorectal cancer (CRC) is the third most diagnosed cancer in men (after prostate and lung cancers) and in women (after breast and lung cancer). It is the second cause of cancer death in men (after lung cancer) and the third one in women (after breast and lung cancers). It is estimated that, in EU-27 countries in 2020, colorectal cancer accounted for 12.7% of all new cancer diagnoses and 12.4% of all deaths due to cancer. Our study aims to assess the opportunistic colorectal cancer screening by colonoscopy in a private hospital. A secondary objective of this study is to analyse the adenoma detection rate (ADR), polyp detection rate (PDR), and colorectal cancer (CRC) detection rate. We designed a retrospective single-centre study in the Gastroenterology Department of Saint Mary Hospital. The study population includes all individuals who performed colonoscopies in 2 years, January 2019–December 2020, addressed to our department by their family physician or came by themselves for a colonoscopy. One thousand seven hundred seventy-eight asymptomatic subjects underwent a colonoscopy for the first time. The mean age was 59.0 ± 10.9, 59.5% female. Eight hundred seventy-three polyps were found in 525 patients. Five hundred and twenty-five had at least one polyp, 185 patients had two polyps, 87 had three polyps, and 40 patients had more than three polyps. The PDR was 49.1%, ADR 39.0%, advanced adenomas in 7.9%, and carcinomas were found in 5.4% of patients. In a country without any colorectal cancer screening policy, polyps were found in almost half of the 1778 asymptomatic patients evaluated in a single private center, 39% of cases adenomas, and 5.4% colorectal cancer. Our study suggests starting screening colonoscopy at the age of 45. A poor bowel preparation significantly impacted the adenoma detection rate. MDPI 2021-12-19 /pmc/articles/PMC8700238/ /pubmed/34943629 http://dx.doi.org/10.3390/diagnostics11122393 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Rațiu, Iulia Lupușoru, Raluca Vora, Prateek Popescu, Alina Sporea, Ioan Goldiș, Adrian Dănilă, Mirela Miuțescu, Bogdan Barbulescu, Andreea Hnatiuc, Madalina Diaconescu, Razvan Tăban, Sorina Lazar, Fulger Șirli, Roxana Opportunistic Colonoscopy Cancer Screening Pays off in Romania—A Single-Centre Study |
title | Opportunistic Colonoscopy Cancer Screening Pays off in Romania—A Single-Centre Study |
title_full | Opportunistic Colonoscopy Cancer Screening Pays off in Romania—A Single-Centre Study |
title_fullStr | Opportunistic Colonoscopy Cancer Screening Pays off in Romania—A Single-Centre Study |
title_full_unstemmed | Opportunistic Colonoscopy Cancer Screening Pays off in Romania—A Single-Centre Study |
title_short | Opportunistic Colonoscopy Cancer Screening Pays off in Romania—A Single-Centre Study |
title_sort | opportunistic colonoscopy cancer screening pays off in romania—a single-centre study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700238/ https://www.ncbi.nlm.nih.gov/pubmed/34943629 http://dx.doi.org/10.3390/diagnostics11122393 |
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