Cargando…

MXD3 Promotes Obesity and the Androgen Receptor Signaling Pathway in Gender-Disparity Hepatocarcinogenesis

Obesity is closely linked to metabolic diseases, particularly non-alcoholic steatohepatitis (NASH) or non-alcoholic fatty liver disease (NAFLD), ultimately leading to hepatocellular carcinoma (HCC). However, the molecular mechanisms of NASH-associated HCC (NAHCC) remain elusive. To explore the impac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tsai, Yi-Wen, Jeng, Kuo-Shyang, He, Mu-Kuang, Hsieh, Yang-Wen, Lai, Hsin-Hung, Lai, Chi-Yu, Huang, Chun-Chieh, Chang, Chiung-Fang, Huang, Chung-Tsui, Her, Guor Mour
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700344/ https://www.ncbi.nlm.nih.gov/pubmed/34943942 http://dx.doi.org/10.3390/cells10123434

Ejemplares similares

Depletion of Alpha-Melanocyte-Stimulating Hormone Induces Insatiable Appetite and Gains in Energy Reserves and Body Weight in Zebrafish
por: Hsieh, Yang-Wen, et al.
Publicado: (2021)

AgRP Neuron-Specific Ablation Represses Appetite, Energy Intake, and Somatic Growth in Larval Zebrafish
por: Lin, Chiu-Ya, et al.
Publicado: (2023)

Deficiency of Adipose Triglyceride Lipase Induces Metabolic Syndrome and Cardiomyopathy in Zebrafish
por: Lai, Hsin-Hung, et al.
Publicado: (2022)

MicroRNA-21 Plays Multiple Oncometabolic Roles in the Process of NAFLD-Related Hepatocellular Carcinoma via PI3K/AKT, TGF-β, and STAT3 Signaling
por: Lai, Chi-Yu, et al.
Publicado: (2021)

Correction: Lai et al. MicroRNA-21 Plays Multiple Oncometabolic Roles in the Process of NAFLD-Related Hepatocellular Carcinoma via PI3K/AKT, TGF-β, and STAT3 Signaling. Cancers 2021, 13, 940
por: Lai, Chi-Yu, et al.
Publicado: (2022)

Alternative Splicing of MXD3 and Its Regulation of MXD3 Levels in Glioblastoma
por: Ngo, Tin, et al.
Publicado: (2019)

MicroRNA-27b Depletion Enhances Endotrophic and Intravascular Lipid Accumulation and Induces Adipocyte Hyperplasia in Zebrafish
por: Hsu, Chia-Chun, et al.
Publicado: (2017)

ATF4 overexpression induces early onset of hyperlipidaemia and hepatic steatosis and enhances adipogenesis in zebrafish
por: Yeh, Kun-Yun, et al.
Publicado: (2017)

MicroRNA-21 Plays Multiple Oncometabolic Roles in Colitis-Associated Carcinoma and Colorectal Cancer via the PI3K/AKT, STAT3, and PDCD4/TNF-α Signaling Pathways in Zebrafish
por: Lai, Chi-Yu, et al.
Publicado: (2021)

Role of MXD3 in Proliferation of DAOY Human Medulloblastoma Cells
por: Barisone, Gustavo A., et al.
Publicado: (2012)

MXD3 as an Immunological and Prognostic Factor From Pancancer Analysis
por: Zhang, Xiaoyu, et al.
Publicado: (2021)

Betanodavirus Induces Oxidative Stress-Mediated Cell Death That Prevented by Anti-Oxidants and Zfcatalase in Fish Cells
por: Chang, Chih-Wei, et al.
Publicado: (2011)

SIRT1 regulates Mxd1 during malignant melanoma progression
por: Meliso, Fabiana M., et al.
Publicado: (2017)

Corrigendum: MXD3 as an Immunological and Prognostic Factor From Pancancer Analysis
por: Zhang, Xiaoyu, et al.
Publicado: (2021)

MXD3 regulation of DAOY cell proliferation dictated by time course of activation
por: Ngo, Tin, et al.
Publicado: (2014)

MXD1 localizes in the nucleolus, binds UBF and impairs rRNA synthesis
por: Lafita-Navarro, Maria del Carmen, et al.
Publicado: (2016)

The MYCL and MXD1 transcription factors regulate the fitness of murine dendritic cells
por: Anderson, David A., et al.
Publicado: (2020)

Expression profiles of the MXD3 gene and association of sequence variants with growth traits in Xianan and Qinchuan cattle
por: Hao, Dan, et al.
Publicado: (2020)

Novel Targeted Therapy for Neuroblastoma: Silencing the MXD3 Gene Using siRNA
por: Duong, Connie, et al.
Publicado: (2017)

An MXD1-derived repressor peptide identifies noncoding mediators of MYC-driven cell proliferation
por: Raffeiner, Philipp, et al.
Publicado: (2020)

HOXA5 inhibits the proliferation of extrahepatic cholangiocarcinoma cells by enhancing MXD1 expression and activating the p53 pathway
por: Xiong, Fei, et al.
Publicado: (2022)

Gender and regional disparities of tuberculosis in Hunan, China
por: Chen, Mengshi, et al.
Publicado: (2014)

Synthesis, Structure, and Tunability of Zero-Dimensional Organic–Inorganic Metal Halides Utilizing the m-Xylylenediammonium Cation: MXD(2)PbI(6), MXDBiI(5), and MXD(3)Bi(2)Br(12)·2H(2)O
por: Klee, Pia S., et al.
Publicado: (2022)

Gender and sex disparity in cancer trials
por: Lee, Eudocia, et al.
Publicado: (2020)

Targeting UHRF1-SAP30-MXD4 axis for leukemia initiating cell eradication in myeloid leukemia
por: Hu, Cheng-Long, et al.
Publicado: (2022)

Alcohol and hepatocarcinogenesis
por: Taniai, Makiko
Publicado: (2020)

Androgen receptor variant 7 exacerbates hepatocarcinogenesis in a c-MYC-driven mouse HCC model
por: Kido, Tatsuo, et al.
Publicado: (2023)

Molecular Targets in Hepatocarcinogenesis and Implications for Therapy
por: Wu, Meng-Yu, et al.
Publicado: (2018)

Proteomic analysis revealed common, unique and systemic signatures in gender-dependent hepatocarcinogenesis
por: Li, Huiling, et al.
Publicado: (2020)

Liver collision tumor of primary hepatocellular carcinoma and neuroendocrine carcinoma: A rare case report
por: Jeng, Kuo-Shyang, et al.
Publicado: (2022)

CPAP enhances and maintains chronic inflammation in hepatocytes to promote hepatocarcinogenesis
por: Chen, Ruo-Yu, et al.
Publicado: (2021)

PRAS40 hyperexpression promotes hepatocarcinogenesis
por: Qi, Zhaolai, et al.
Publicado: (2020)

MiR-19a/b modulate the metastasis of gastric cancer cells by targeting the tumour suppressor MXD1
por: Wu, Q, et al.
Publicado: (2014)

miR-19a/b modulates lung cancer cells metastasis through suppression of MXD1 expression
por: Hu, Wenxia, et al.
Publicado: (2016)

Novel MXD4–NUTM1 fusion transcript identified in primary ovarian undifferentiated small round cell sarcoma
por: Tamura, Ryo, et al.
Publicado: (2018)

Overexpression of MAX dimerization protein 3 (MXD3) predicts poor prognosis in clear cell renal cell carcinoma
por: Zhang, Fangyuan, et al.
Publicado: (2021)

Androgen Receptor (AR)-TLR4 Crosstalk Mediates Gender Disparities in Hepatocellular Carcinoma Incidence and Progression
por: Han, Qiuju, et al.
Publicado: (2020)

Azido(benzonitrile-κN)[hydridotris(pyrazol-1-yl-κN (2))borato](triphenylphosphine-κP)ruthenium(II)
por: Huang, Chiung-Cheng, et al.
Publicado: (2010)

Methyl 1-benzyl-1H-1,2,3-triazole-4-carboxylate
por: Huang, Chiung-Cheng, et al.
Publicado: (2010)

Loss of stromal androgen receptor leads to suppressed prostate tumourigenesis via modulation of pro-inflammatory cytokines/chemokines
por: Lai, Kuo-Pao, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_6kkeql699vc1qcfvejk8uupg65