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Male Breast Cancer Review. A Rare Case of Pure DCIS: Imaging Protocol, Radiomics and Management
Ductal carcinoma in situ (DCIS) of male breast is a rare lesion, often associated with invasive carcinoma. When the in situ component is present in pure form, histological grade is usually low or intermediate. Imaging is difficult as gynaecomastia is often present and can mask underlying findings. W...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700459/ https://www.ncbi.nlm.nih.gov/pubmed/34943439 http://dx.doi.org/10.3390/diagnostics11122199 |
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author | Tari, Daniele Ugo Morelli, Luigi Guida, Antonella Pinto, Fabio |
author_facet | Tari, Daniele Ugo Morelli, Luigi Guida, Antonella Pinto, Fabio |
author_sort | Tari, Daniele Ugo |
collection | PubMed |
description | Ductal carcinoma in situ (DCIS) of male breast is a rare lesion, often associated with invasive carcinoma. When the in situ component is present in pure form, histological grade is usually low or intermediate. Imaging is difficult as gynaecomastia is often present and can mask underlying findings. We report a rare case of pure high-grade DCIS in a young male patient, with associated intraductal papilloma and atypical ductal hyperplasia. Digital breast tomosynthesis (DBT) showed an area of architectural distortion at the union of outer quadrants of the left breast without gynaecomastia. Triple assessment suggested performing a nipple-sparing mastectomy, which revealed the presence of a focal area of high-grade DCIS of 2 mm. DCIS, even of high grade, is difficult to detect with mammography and even more rare, especially when associated with other proliferative lesions. DBT with 2D synthetic reconstruction is useful as the imaging step of a triple assessment and it should be performed in both symptomatic and asymptomatic high-risk men to differentiate between malignant and benign lesions. We propose a diagnostic model to early detect breast cancer in men, optimizing resources according to efficiency, effectiveness and economy, and look forward to radiomics as a powerful tool to help radiologists. |
format | Online Article Text |
id | pubmed-8700459 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87004592021-12-24 Male Breast Cancer Review. A Rare Case of Pure DCIS: Imaging Protocol, Radiomics and Management Tari, Daniele Ugo Morelli, Luigi Guida, Antonella Pinto, Fabio Diagnostics (Basel) Case Report Ductal carcinoma in situ (DCIS) of male breast is a rare lesion, often associated with invasive carcinoma. When the in situ component is present in pure form, histological grade is usually low or intermediate. Imaging is difficult as gynaecomastia is often present and can mask underlying findings. We report a rare case of pure high-grade DCIS in a young male patient, with associated intraductal papilloma and atypical ductal hyperplasia. Digital breast tomosynthesis (DBT) showed an area of architectural distortion at the union of outer quadrants of the left breast without gynaecomastia. Triple assessment suggested performing a nipple-sparing mastectomy, which revealed the presence of a focal area of high-grade DCIS of 2 mm. DCIS, even of high grade, is difficult to detect with mammography and even more rare, especially when associated with other proliferative lesions. DBT with 2D synthetic reconstruction is useful as the imaging step of a triple assessment and it should be performed in both symptomatic and asymptomatic high-risk men to differentiate between malignant and benign lesions. We propose a diagnostic model to early detect breast cancer in men, optimizing resources according to efficiency, effectiveness and economy, and look forward to radiomics as a powerful tool to help radiologists. MDPI 2021-11-25 /pmc/articles/PMC8700459/ /pubmed/34943439 http://dx.doi.org/10.3390/diagnostics11122199 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Tari, Daniele Ugo Morelli, Luigi Guida, Antonella Pinto, Fabio Male Breast Cancer Review. A Rare Case of Pure DCIS: Imaging Protocol, Radiomics and Management |
title | Male Breast Cancer Review. A Rare Case of Pure DCIS: Imaging Protocol, Radiomics and Management |
title_full | Male Breast Cancer Review. A Rare Case of Pure DCIS: Imaging Protocol, Radiomics and Management |
title_fullStr | Male Breast Cancer Review. A Rare Case of Pure DCIS: Imaging Protocol, Radiomics and Management |
title_full_unstemmed | Male Breast Cancer Review. A Rare Case of Pure DCIS: Imaging Protocol, Radiomics and Management |
title_short | Male Breast Cancer Review. A Rare Case of Pure DCIS: Imaging Protocol, Radiomics and Management |
title_sort | male breast cancer review. a rare case of pure dcis: imaging protocol, radiomics and management |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700459/ https://www.ncbi.nlm.nih.gov/pubmed/34943439 http://dx.doi.org/10.3390/diagnostics11122199 |
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