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Diagnostics in Patients Suspect for Breast Cancer in The Netherlands

The goal of this study was to describe the variation in hospital-based diagnostic care activities for patients with symptomatology suspect for breast cancer in The Netherlands. Two cohorts were included: the ‘benign’ cohort (30,334 women suspected of, but without breast cancer) and the ‘malignant’ c...

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Autores principales: Voets, Madelon M., Groothuis-Oudshoorn, Catharina G. M., Veneklaas, Liset H. J., Manohar, Srirang, Brinkhuis, Mariël, Veltman, Jeroen, de Munck, Linda, de Geus-Oei, Lioe-Fee, Broeders, Mireille J. M., Siesling, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700505/
https://www.ncbi.nlm.nih.gov/pubmed/34940058
http://dx.doi.org/10.3390/curroncol28060419
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author Voets, Madelon M.
Groothuis-Oudshoorn, Catharina G. M.
Veneklaas, Liset H. J.
Manohar, Srirang
Brinkhuis, Mariël
Veltman, Jeroen
de Munck, Linda
de Geus-Oei, Lioe-Fee
Broeders, Mireille J. M.
Siesling, Sabine
author_facet Voets, Madelon M.
Groothuis-Oudshoorn, Catharina G. M.
Veneklaas, Liset H. J.
Manohar, Srirang
Brinkhuis, Mariël
Veltman, Jeroen
de Munck, Linda
de Geus-Oei, Lioe-Fee
Broeders, Mireille J. M.
Siesling, Sabine
author_sort Voets, Madelon M.
collection PubMed
description The goal of this study was to describe the variation in hospital-based diagnostic care activities for patients with symptomatology suspect for breast cancer in The Netherlands. Two cohorts were included: the ‘benign’ cohort (30,334 women suspected of, but without breast cancer) and the ‘malignant’ cohort (2236 breast cancer patients). Hospital-based financial data was combined with tumor data (malignant cohort) from The Netherlands Cancer Registry. Patterns within diagnostic pathways were analyzed. Factors influencing the number of visits and number of diagnostic care activities until diagnosis were identified in the malignant cohort with multivariable Cox and Poisson regression models. Compared to patients with benign diagnosis, patients with malignant disease received their diagnosis less frequently in one day, after an equal average number of hospital visits and higher average number of diagnostic activities. Factors increasing the number of diagnostic care activities were the following: lower age and higher cM-and cN-stages. Factors increasing the number of days until (malignant) diagnosis were as follows: higher BIRADS-score, screen-detected and higher cN-and cT-stages. Hospital of diagnosis influenced both number of activities and days to diagnosis. The diagnostic care pathway of patients with malignant disease required more time and diagnostic activities than benign disease and depends on hospital, tumor and patient characteristics.
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spelling pubmed-87005052021-12-24 Diagnostics in Patients Suspect for Breast Cancer in The Netherlands Voets, Madelon M. Groothuis-Oudshoorn, Catharina G. M. Veneklaas, Liset H. J. Manohar, Srirang Brinkhuis, Mariël Veltman, Jeroen de Munck, Linda de Geus-Oei, Lioe-Fee Broeders, Mireille J. M. Siesling, Sabine Curr Oncol Article The goal of this study was to describe the variation in hospital-based diagnostic care activities for patients with symptomatology suspect for breast cancer in The Netherlands. Two cohorts were included: the ‘benign’ cohort (30,334 women suspected of, but without breast cancer) and the ‘malignant’ cohort (2236 breast cancer patients). Hospital-based financial data was combined with tumor data (malignant cohort) from The Netherlands Cancer Registry. Patterns within diagnostic pathways were analyzed. Factors influencing the number of visits and number of diagnostic care activities until diagnosis were identified in the malignant cohort with multivariable Cox and Poisson regression models. Compared to patients with benign diagnosis, patients with malignant disease received their diagnosis less frequently in one day, after an equal average number of hospital visits and higher average number of diagnostic activities. Factors increasing the number of diagnostic care activities were the following: lower age and higher cM-and cN-stages. Factors increasing the number of days until (malignant) diagnosis were as follows: higher BIRADS-score, screen-detected and higher cN-and cT-stages. Hospital of diagnosis influenced both number of activities and days to diagnosis. The diagnostic care pathway of patients with malignant disease required more time and diagnostic activities than benign disease and depends on hospital, tumor and patient characteristics. MDPI 2021-11-29 /pmc/articles/PMC8700505/ /pubmed/34940058 http://dx.doi.org/10.3390/curroncol28060419 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Voets, Madelon M.
Groothuis-Oudshoorn, Catharina G. M.
Veneklaas, Liset H. J.
Manohar, Srirang
Brinkhuis, Mariël
Veltman, Jeroen
de Munck, Linda
de Geus-Oei, Lioe-Fee
Broeders, Mireille J. M.
Siesling, Sabine
Diagnostics in Patients Suspect for Breast Cancer in The Netherlands
title Diagnostics in Patients Suspect for Breast Cancer in The Netherlands
title_full Diagnostics in Patients Suspect for Breast Cancer in The Netherlands
title_fullStr Diagnostics in Patients Suspect for Breast Cancer in The Netherlands
title_full_unstemmed Diagnostics in Patients Suspect for Breast Cancer in The Netherlands
title_short Diagnostics in Patients Suspect for Breast Cancer in The Netherlands
title_sort diagnostics in patients suspect for breast cancer in the netherlands
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700505/
https://www.ncbi.nlm.nih.gov/pubmed/34940058
http://dx.doi.org/10.3390/curroncol28060419
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