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The PGRMC1 Antagonist AG-205 Inhibits Synthesis of Galactosylceramide and Sulfatide

Sulfatide synthesis in the human renal cancer cell line SMKT-R3 was strongly inhibited in the presence of low µM concentrations of AG-205, a progesterone receptor membrane component 1 (PGRMC1) antagonist. This was also the case in Chinese hamster ovary (CHO) cells stably transfected with UDP-galacto...

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Detalles Bibliográficos
Autores principales: Wang-Eckhardt, Lihua, Becker, Ivonne, Eckhardt, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700550/
https://www.ncbi.nlm.nih.gov/pubmed/34944026
http://dx.doi.org/10.3390/cells10123520