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Differential Dose- and Tissue-Dependent Effects of foxo on Aging, Metabolic and Proteostatic Pathways
Aging is the gradual deterioration of physiological functions that culminates in death. Several studies across a wide range of model organisms have revealed the involvement of FOXO (forkhead box, class O) transcription factors in orchestrating metabolic homeostasis, as well as in regulating longevit...
Autores principales: | Manola, Maria S., Gumeni, Sentiljana, Trougakos, Ioannis P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700554/ https://www.ncbi.nlm.nih.gov/pubmed/34944088 http://dx.doi.org/10.3390/cells10123577 |
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