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Immunoglobulin A Mucosal Immunity and Altered Respiratory Epithelium in Cystic Fibrosis

The respiratory epithelium represents the first chemical, immune, and physical barrier against inhaled noxious materials, particularly pathogens in cystic fibrosis. Local mucus thickening, altered mucociliary clearance, and reduced pH due to CFTR protein dysfunction favor bacterial overgrowth and ex...

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Detalles Bibliográficos
Autores principales: Gohy, Sophie, Moeremans, Alexandra, Pilette, Charles, Collin, Amandine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700636/
https://www.ncbi.nlm.nih.gov/pubmed/34944110
http://dx.doi.org/10.3390/cells10123603