Shear Stress Alterations Activate BMP4/pSMAD5 Signaling and Induce Endothelial Mesenchymal Transition in Varicose Veins

Chronic venous diseases, including varicose veins, are characterized by hemodynamic disturbances due to valve defects, venous insufficiency, and orthostatism. Veins are physiologically low shear stress systems, and how altered hemodynamics drives focal endothelial dysfunction and causes venous remod...

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Detalles Bibliográficos
Autores principales: Chandran Latha, Karthika, Sreekumar, Ahalya, Beena, Vyshna, S.S., Binil Raj, Lakkappa, RaviKumar B., Kalyani, Ravi, Nair, Radhakrishnan, Kalpana, Saligrama Ramegowda, Kartha, Chandrasekharan C., Surendran, Sumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700678/
https://www.ncbi.nlm.nih.gov/pubmed/34944071
http://dx.doi.org/10.3390/cells10123563

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