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Validity and Prognostic Value of a Polygenic Risk Score for Parkinson’s Disease

Idiopathic Parkinson’s disease (PD) is a complex multifactorial disorder caused by the interplay of both genetic and non-genetic risk factors. Polygenic risk scores (PRSs) are one way to aggregate the effects of a large number of genetic variants upon the risk for a disease like PD in a single quant...

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Detalles Bibliográficos
Autores principales:	Koch, Sebastian, Laabs, Björn-Hergen, Kasten, Meike, Vollstedt, Eva-Juliane, Becktepe, Jos, Brüggemann, Norbert, Franke, Andre, Krämer, Ulrike M., Kuhlenbäumer, Gregor, Lieb, Wolfgang, Mollenhauer, Brit, Neis, Miriam, Trenkwalder, Claudia, Schäffer, Eva, Usnich, Tatiana, Wittig, Michael, Klein, Christine, König, Inke R., Lohmann, Katja, Krawczak, Michael, Caliebe, Amke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700849/ https://www.ncbi.nlm.nih.gov/pubmed/34946808 http://dx.doi.org/10.3390/genes12121859

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