Genome-Wide Analyses for Osteosarcoma in Leonberger Dogs Reveal the CDKN2A/B Gene Locus as a Major Risk Locus

Dogs represent a unique spontaneous cancer model. Osteosarcoma (OSA) is the most common primary bone tumor in dogs (OMIA 001441-9615), and strongly resembles human forms of OSA. Several large- to giant-sized dog breeds, including the Leonberger, have a greatly increased risk of developing OSA. We pe...

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Detalles Bibliográficos
Autores principales: Letko, Anna, Minor, Katie M., Norton, Elaine M., Marinescu, Voichita D., Drögemüller, Michaela, Ivansson, Emma, Megquier, Kate, Noh, Hyun Ji, Starkey, Mike, Friedenberg, Steven G., Lindblad-Toh, Kerstin, Mickelson, James R., Drögemüller, Cord
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700858/
https://www.ncbi.nlm.nih.gov/pubmed/34946912
http://dx.doi.org/10.3390/genes12121964

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