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Spatial and Temporal Expression of High-Mobility-Group Nucleosome-Binding (HMGN) Genes in Brain Areas Associated with Cognition in Individuals with Down Syndrome

DNA methylation and histone posttranslational modifications are epigenetics processes that contribute to neurophenotype of Down Syndrome (DS). Previous reports present strong evidence that nonhistone high-mobility-group N proteins (HMGN) are epigenetic regulators. They play important functions in va...

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Detalles Bibliográficos
Autores principales: Rodríguez-Ortiz, Alejandra, Montoya-Villegas, Julio César, García-Vallejo, Felipe, Mina-Paz, Yecid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8700945/
https://www.ncbi.nlm.nih.gov/pubmed/34946949
http://dx.doi.org/10.3390/genes12122000