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Next Generation Sequencing Identifies the HLA-DQA1*03:03 Allele in the Type 1 Diabetes Risk-Associated HLA-DQ8 Serotype

The highest genetic type 1 diabetes risk is conferred by HLA class II haplotypes defined by alleles at the HLA-DR and -DQ loci. The combination of HLA-DQA1*03:01 and DQB1*03:02 alleles (summarized as ‘HLA-DQ8′) is reported to be among the two most prevalent HLA class II haplotypes in Caucasian type...

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Detalles Bibliográficos
Autores principales:	Enczmann, Jürgen, Balz, Vera, Hoffmann, Maximilian, Kummer, Sebastian, Reinauer, Christina, Döing, Carsten, Förtsch, Katharina, Welters, Alena, Mayatepek, Ertan, Meissner, Thomas, Jacobsen, Marc, Seyfarth, Julia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8701008/ https://www.ncbi.nlm.nih.gov/pubmed/34946827 http://dx.doi.org/10.3390/genes12121879

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