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Acrylamide in Baby Foods: A Probabilistic Exposure Assessment
Acrylamide (also known as 2-propenamide) (AA) is a toxicant that develops in food during high-temperature cooking, and its occurrence is common in biscuits and baked snacks. AA is known for its in vivo neurotoxic and carcinogenic effects, and it is considered a potential carcinogen for humans. Infan...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8701054/ https://www.ncbi.nlm.nih.gov/pubmed/34945452 http://dx.doi.org/10.3390/foods10122900 |
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author | Esposito, Francesco Nolasco, Agata Caracciolo, Francesco Velotto, Salvatore Montuori, Paolo Romano, Raffaele Stasi, Tommaso Cirillo, Teresa |
author_facet | Esposito, Francesco Nolasco, Agata Caracciolo, Francesco Velotto, Salvatore Montuori, Paolo Romano, Raffaele Stasi, Tommaso Cirillo, Teresa |
author_sort | Esposito, Francesco |
collection | PubMed |
description | Acrylamide (also known as 2-propenamide) (AA) is a toxicant that develops in food during high-temperature cooking, and its occurrence is common in biscuits and baked snacks. AA is known for its in vivo neurotoxic and carcinogenic effects, and it is considered a potential carcinogen for humans. Infants may be exposed to AA as early as during weaning through baked food such as biscuits. This study set out to ascertain the concentration of AA in food products intended for infants to assess the dietary exposure to this food contaminant. AA levels were determined through GC/MS and bromination, and dietary exposure was evaluated by a probabilistic method based on Monte Carlo simulation. The results showed that the probability of a carcinogenic exposure is 94%, 92%, and 87%, respectively, for 6-, 12-, and 18-months infants, suggesting the need to delay the introduction of baked products in the diet of weaned infants. It should be noted, however, that these conclusions were drawn considering the biscuits as the primary source of exposure. |
format | Online Article Text |
id | pubmed-8701054 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87010542021-12-24 Acrylamide in Baby Foods: A Probabilistic Exposure Assessment Esposito, Francesco Nolasco, Agata Caracciolo, Francesco Velotto, Salvatore Montuori, Paolo Romano, Raffaele Stasi, Tommaso Cirillo, Teresa Foods Article Acrylamide (also known as 2-propenamide) (AA) is a toxicant that develops in food during high-temperature cooking, and its occurrence is common in biscuits and baked snacks. AA is known for its in vivo neurotoxic and carcinogenic effects, and it is considered a potential carcinogen for humans. Infants may be exposed to AA as early as during weaning through baked food such as biscuits. This study set out to ascertain the concentration of AA in food products intended for infants to assess the dietary exposure to this food contaminant. AA levels were determined through GC/MS and bromination, and dietary exposure was evaluated by a probabilistic method based on Monte Carlo simulation. The results showed that the probability of a carcinogenic exposure is 94%, 92%, and 87%, respectively, for 6-, 12-, and 18-months infants, suggesting the need to delay the introduction of baked products in the diet of weaned infants. It should be noted, however, that these conclusions were drawn considering the biscuits as the primary source of exposure. MDPI 2021-11-23 /pmc/articles/PMC8701054/ /pubmed/34945452 http://dx.doi.org/10.3390/foods10122900 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Esposito, Francesco Nolasco, Agata Caracciolo, Francesco Velotto, Salvatore Montuori, Paolo Romano, Raffaele Stasi, Tommaso Cirillo, Teresa Acrylamide in Baby Foods: A Probabilistic Exposure Assessment |
title | Acrylamide in Baby Foods: A Probabilistic Exposure Assessment |
title_full | Acrylamide in Baby Foods: A Probabilistic Exposure Assessment |
title_fullStr | Acrylamide in Baby Foods: A Probabilistic Exposure Assessment |
title_full_unstemmed | Acrylamide in Baby Foods: A Probabilistic Exposure Assessment |
title_short | Acrylamide in Baby Foods: A Probabilistic Exposure Assessment |
title_sort | acrylamide in baby foods: a probabilistic exposure assessment |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8701054/ https://www.ncbi.nlm.nih.gov/pubmed/34945452 http://dx.doi.org/10.3390/foods10122900 |
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