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Recent Advances in the Mechanisms and Regulation of QS in Dairy Spoilage by Pseudomonas spp.

Food spoilage is a serious issue dramatically impacting the worldwide need to counteract food insecurity. Despite the very expensive application of low temperatures, the proper conservation of fresh dairy products is continuously threatened at different stages of production and commercialization by...

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Autores principales: Quintieri, Laura, Caputo, Leonardo, Brasca, Milena, Fanelli, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8701193/
https://www.ncbi.nlm.nih.gov/pubmed/34945641
http://dx.doi.org/10.3390/foods10123088
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author Quintieri, Laura
Caputo, Leonardo
Brasca, Milena
Fanelli, Francesca
author_facet Quintieri, Laura
Caputo, Leonardo
Brasca, Milena
Fanelli, Francesca
author_sort Quintieri, Laura
collection PubMed
description Food spoilage is a serious issue dramatically impacting the worldwide need to counteract food insecurity. Despite the very expensive application of low temperatures, the proper conservation of fresh dairy products is continuously threatened at different stages of production and commercialization by psychrotrophic populations mainly belonging to the Pseudomonas genus. These bacteria cause discolouration, loss of structure, and off-flavours, with fatal implications on the quality and shelf-life of products. While the effects of pseudomonad decay have been widely reported, the mechanisms responsible for the activation and regulation of spoilage pathways are still poorly explored. Recently, molecule signals and regulators involved in quorum sensing (QS), such as homoserine lactones, the luxR/luxI system, hdtS, and psoR, have been detected in spoiled products and bacterial spoiler species; this evidence suggests the role of bacterial cross talk in dairy spoilage and paves the way towards the search for novel preservation strategies based on QS inhibition. The aim of this review was to investigate the advancements achieved by the application of omic approaches in deciphering the molecular mechanisms controlled by QS systems in pseudomonads, by focusing on the regulators and metabolic pathways responsible for spoilage of fresh dairy products. In addition, due the ability of pseudomonads to quickly spread in the environment as biofilm communities, which may also include pathogenic and multidrug-resistant (MDR) species, the risk derived from the gaps in clearly defined and regulated sanitization actions is underlined.
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spelling pubmed-87011932021-12-24 Recent Advances in the Mechanisms and Regulation of QS in Dairy Spoilage by Pseudomonas spp. Quintieri, Laura Caputo, Leonardo Brasca, Milena Fanelli, Francesca Foods Review Food spoilage is a serious issue dramatically impacting the worldwide need to counteract food insecurity. Despite the very expensive application of low temperatures, the proper conservation of fresh dairy products is continuously threatened at different stages of production and commercialization by psychrotrophic populations mainly belonging to the Pseudomonas genus. These bacteria cause discolouration, loss of structure, and off-flavours, with fatal implications on the quality and shelf-life of products. While the effects of pseudomonad decay have been widely reported, the mechanisms responsible for the activation and regulation of spoilage pathways are still poorly explored. Recently, molecule signals and regulators involved in quorum sensing (QS), such as homoserine lactones, the luxR/luxI system, hdtS, and psoR, have been detected in spoiled products and bacterial spoiler species; this evidence suggests the role of bacterial cross talk in dairy spoilage and paves the way towards the search for novel preservation strategies based on QS inhibition. The aim of this review was to investigate the advancements achieved by the application of omic approaches in deciphering the molecular mechanisms controlled by QS systems in pseudomonads, by focusing on the regulators and metabolic pathways responsible for spoilage of fresh dairy products. In addition, due the ability of pseudomonads to quickly spread in the environment as biofilm communities, which may also include pathogenic and multidrug-resistant (MDR) species, the risk derived from the gaps in clearly defined and regulated sanitization actions is underlined. MDPI 2021-12-13 /pmc/articles/PMC8701193/ /pubmed/34945641 http://dx.doi.org/10.3390/foods10123088 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Quintieri, Laura
Caputo, Leonardo
Brasca, Milena
Fanelli, Francesca
Recent Advances in the Mechanisms and Regulation of QS in Dairy Spoilage by Pseudomonas spp.
title Recent Advances in the Mechanisms and Regulation of QS in Dairy Spoilage by Pseudomonas spp.
title_full Recent Advances in the Mechanisms and Regulation of QS in Dairy Spoilage by Pseudomonas spp.
title_fullStr Recent Advances in the Mechanisms and Regulation of QS in Dairy Spoilage by Pseudomonas spp.
title_full_unstemmed Recent Advances in the Mechanisms and Regulation of QS in Dairy Spoilage by Pseudomonas spp.
title_short Recent Advances in the Mechanisms and Regulation of QS in Dairy Spoilage by Pseudomonas spp.
title_sort recent advances in the mechanisms and regulation of qs in dairy spoilage by pseudomonas spp.
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8701193/
https://www.ncbi.nlm.nih.gov/pubmed/34945641
http://dx.doi.org/10.3390/foods10123088
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