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Whole Three-Dimensional Dosimetry of Carbon Ion Beams with an MRI-Based Nanocomposite Fricke Gel Dosimeter Using Rapid T(1) Mapping Method

MRI-based gel dosimeters are attractive systems for the evaluation of complex dose distributions in radiotherapy. In particular, the nanocomposite Fricke gel dosimeter is one among a few dosimeters capable of accurately evaluating the dose distribution of heavy ion beams. In contrast, reduction of t...

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Autores principales: Mizukami, Shinya, Watanabe, Yusuke, Mizoguchi, Takahiro, Gomi, Tsutomu, Hara, Hidetake, Takei, Hideyuki, Fukunishi, Nobuhisa, Ishikawa, Kenichi L., Fukuda, Shigekazu, Maeyama, Takuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8701283/
https://www.ncbi.nlm.nih.gov/pubmed/34940293
http://dx.doi.org/10.3390/gels7040233
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author Mizukami, Shinya
Watanabe, Yusuke
Mizoguchi, Takahiro
Gomi, Tsutomu
Hara, Hidetake
Takei, Hideyuki
Fukunishi, Nobuhisa
Ishikawa, Kenichi L.
Fukuda, Shigekazu
Maeyama, Takuya
author_facet Mizukami, Shinya
Watanabe, Yusuke
Mizoguchi, Takahiro
Gomi, Tsutomu
Hara, Hidetake
Takei, Hideyuki
Fukunishi, Nobuhisa
Ishikawa, Kenichi L.
Fukuda, Shigekazu
Maeyama, Takuya
author_sort Mizukami, Shinya
collection PubMed
description MRI-based gel dosimeters are attractive systems for the evaluation of complex dose distributions in radiotherapy. In particular, the nanocomposite Fricke gel dosimeter is one among a few dosimeters capable of accurately evaluating the dose distribution of heavy ion beams. In contrast, reduction of the scanning time is a challenging issue for the acquisition of three-dimensional volume data. In this study, we investigated a three-dimensional dose distribution measurement method for heavy ion beams using variable flip angle (VFA), which is expected to significantly reduce the MRI scanning time. Our findings clarified that the whole three-dimensional dose distribution could be evaluated within the conventional imaging time (20 min) and quality of one cross-section.
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spelling pubmed-87012832021-12-24 Whole Three-Dimensional Dosimetry of Carbon Ion Beams with an MRI-Based Nanocomposite Fricke Gel Dosimeter Using Rapid T(1) Mapping Method Mizukami, Shinya Watanabe, Yusuke Mizoguchi, Takahiro Gomi, Tsutomu Hara, Hidetake Takei, Hideyuki Fukunishi, Nobuhisa Ishikawa, Kenichi L. Fukuda, Shigekazu Maeyama, Takuya Gels Article MRI-based gel dosimeters are attractive systems for the evaluation of complex dose distributions in radiotherapy. In particular, the nanocomposite Fricke gel dosimeter is one among a few dosimeters capable of accurately evaluating the dose distribution of heavy ion beams. In contrast, reduction of the scanning time is a challenging issue for the acquisition of three-dimensional volume data. In this study, we investigated a three-dimensional dose distribution measurement method for heavy ion beams using variable flip angle (VFA), which is expected to significantly reduce the MRI scanning time. Our findings clarified that the whole three-dimensional dose distribution could be evaluated within the conventional imaging time (20 min) and quality of one cross-section. MDPI 2021-11-25 /pmc/articles/PMC8701283/ /pubmed/34940293 http://dx.doi.org/10.3390/gels7040233 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Mizukami, Shinya
Watanabe, Yusuke
Mizoguchi, Takahiro
Gomi, Tsutomu
Hara, Hidetake
Takei, Hideyuki
Fukunishi, Nobuhisa
Ishikawa, Kenichi L.
Fukuda, Shigekazu
Maeyama, Takuya
Whole Three-Dimensional Dosimetry of Carbon Ion Beams with an MRI-Based Nanocomposite Fricke Gel Dosimeter Using Rapid T(1) Mapping Method
title Whole Three-Dimensional Dosimetry of Carbon Ion Beams with an MRI-Based Nanocomposite Fricke Gel Dosimeter Using Rapid T(1) Mapping Method
title_full Whole Three-Dimensional Dosimetry of Carbon Ion Beams with an MRI-Based Nanocomposite Fricke Gel Dosimeter Using Rapid T(1) Mapping Method
title_fullStr Whole Three-Dimensional Dosimetry of Carbon Ion Beams with an MRI-Based Nanocomposite Fricke Gel Dosimeter Using Rapid T(1) Mapping Method
title_full_unstemmed Whole Three-Dimensional Dosimetry of Carbon Ion Beams with an MRI-Based Nanocomposite Fricke Gel Dosimeter Using Rapid T(1) Mapping Method
title_short Whole Three-Dimensional Dosimetry of Carbon Ion Beams with an MRI-Based Nanocomposite Fricke Gel Dosimeter Using Rapid T(1) Mapping Method
title_sort whole three-dimensional dosimetry of carbon ion beams with an mri-based nanocomposite fricke gel dosimeter using rapid t(1) mapping method
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8701283/
https://www.ncbi.nlm.nih.gov/pubmed/34940293
http://dx.doi.org/10.3390/gels7040233
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