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Whole Three-Dimensional Dosimetry of Carbon Ion Beams with an MRI-Based Nanocomposite Fricke Gel Dosimeter Using Rapid T(1) Mapping Method
MRI-based gel dosimeters are attractive systems for the evaluation of complex dose distributions in radiotherapy. In particular, the nanocomposite Fricke gel dosimeter is one among a few dosimeters capable of accurately evaluating the dose distribution of heavy ion beams. In contrast, reduction of t...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8701283/ https://www.ncbi.nlm.nih.gov/pubmed/34940293 http://dx.doi.org/10.3390/gels7040233 |
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author | Mizukami, Shinya Watanabe, Yusuke Mizoguchi, Takahiro Gomi, Tsutomu Hara, Hidetake Takei, Hideyuki Fukunishi, Nobuhisa Ishikawa, Kenichi L. Fukuda, Shigekazu Maeyama, Takuya |
author_facet | Mizukami, Shinya Watanabe, Yusuke Mizoguchi, Takahiro Gomi, Tsutomu Hara, Hidetake Takei, Hideyuki Fukunishi, Nobuhisa Ishikawa, Kenichi L. Fukuda, Shigekazu Maeyama, Takuya |
author_sort | Mizukami, Shinya |
collection | PubMed |
description | MRI-based gel dosimeters are attractive systems for the evaluation of complex dose distributions in radiotherapy. In particular, the nanocomposite Fricke gel dosimeter is one among a few dosimeters capable of accurately evaluating the dose distribution of heavy ion beams. In contrast, reduction of the scanning time is a challenging issue for the acquisition of three-dimensional volume data. In this study, we investigated a three-dimensional dose distribution measurement method for heavy ion beams using variable flip angle (VFA), which is expected to significantly reduce the MRI scanning time. Our findings clarified that the whole three-dimensional dose distribution could be evaluated within the conventional imaging time (20 min) and quality of one cross-section. |
format | Online Article Text |
id | pubmed-8701283 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-87012832021-12-24 Whole Three-Dimensional Dosimetry of Carbon Ion Beams with an MRI-Based Nanocomposite Fricke Gel Dosimeter Using Rapid T(1) Mapping Method Mizukami, Shinya Watanabe, Yusuke Mizoguchi, Takahiro Gomi, Tsutomu Hara, Hidetake Takei, Hideyuki Fukunishi, Nobuhisa Ishikawa, Kenichi L. Fukuda, Shigekazu Maeyama, Takuya Gels Article MRI-based gel dosimeters are attractive systems for the evaluation of complex dose distributions in radiotherapy. In particular, the nanocomposite Fricke gel dosimeter is one among a few dosimeters capable of accurately evaluating the dose distribution of heavy ion beams. In contrast, reduction of the scanning time is a challenging issue for the acquisition of three-dimensional volume data. In this study, we investigated a three-dimensional dose distribution measurement method for heavy ion beams using variable flip angle (VFA), which is expected to significantly reduce the MRI scanning time. Our findings clarified that the whole three-dimensional dose distribution could be evaluated within the conventional imaging time (20 min) and quality of one cross-section. MDPI 2021-11-25 /pmc/articles/PMC8701283/ /pubmed/34940293 http://dx.doi.org/10.3390/gels7040233 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Mizukami, Shinya Watanabe, Yusuke Mizoguchi, Takahiro Gomi, Tsutomu Hara, Hidetake Takei, Hideyuki Fukunishi, Nobuhisa Ishikawa, Kenichi L. Fukuda, Shigekazu Maeyama, Takuya Whole Three-Dimensional Dosimetry of Carbon Ion Beams with an MRI-Based Nanocomposite Fricke Gel Dosimeter Using Rapid T(1) Mapping Method |
title | Whole Three-Dimensional Dosimetry of Carbon Ion Beams with an MRI-Based Nanocomposite Fricke Gel Dosimeter Using Rapid T(1) Mapping Method |
title_full | Whole Three-Dimensional Dosimetry of Carbon Ion Beams with an MRI-Based Nanocomposite Fricke Gel Dosimeter Using Rapid T(1) Mapping Method |
title_fullStr | Whole Three-Dimensional Dosimetry of Carbon Ion Beams with an MRI-Based Nanocomposite Fricke Gel Dosimeter Using Rapid T(1) Mapping Method |
title_full_unstemmed | Whole Three-Dimensional Dosimetry of Carbon Ion Beams with an MRI-Based Nanocomposite Fricke Gel Dosimeter Using Rapid T(1) Mapping Method |
title_short | Whole Three-Dimensional Dosimetry of Carbon Ion Beams with an MRI-Based Nanocomposite Fricke Gel Dosimeter Using Rapid T(1) Mapping Method |
title_sort | whole three-dimensional dosimetry of carbon ion beams with an mri-based nanocomposite fricke gel dosimeter using rapid t(1) mapping method |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8701283/ https://www.ncbi.nlm.nih.gov/pubmed/34940293 http://dx.doi.org/10.3390/gels7040233 |
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