Structural Insight into the Mechanism of PALB2 Interaction with MRG15

The tumor suppressor protein partner and localizer of BRCA2 (PALB2) orchestrates the interactions between breast cancer susceptibility proteins 1 and 2 (BRCA1, -2) that are critical for genome stability, homologous recombination (HR) and DNA repair. PALB2 mutations predispose patients to a spectrum...

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Detalles Bibliográficos
Autores principales: Redington, Jennifer, Deveryshetty, Jaigeeth, Kanikkannan, Lakshmi, Miller, Ian, Korolev, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8701324/
https://www.ncbi.nlm.nih.gov/pubmed/34946951
http://dx.doi.org/10.3390/genes12122002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8701324/
https://www.ncbi.nlm.nih.gov/pubmed/34946951
http://dx.doi.org/10.3390/genes12122002

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