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Structural Insight into the Mechanism of PALB2 Interaction with MRG15
The tumor suppressor protein partner and localizer of BRCA2 (PALB2) orchestrates the interactions between breast cancer susceptibility proteins 1 and 2 (BRCA1, -2) that are critical for genome stability, homologous recombination (HR) and DNA repair. PALB2 mutations predispose patients to a spectrum...
Autores principales: | Redington, Jennifer, Deveryshetty, Jaigeeth, Kanikkannan, Lakshmi, Miller, Ian, Korolev, Sergey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8701324/ https://www.ncbi.nlm.nih.gov/pubmed/34946951 http://dx.doi.org/10.3390/genes12122002 |
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