Cargando…
Inhibition of Sars-Cov-2 Viral Replication and In Vivo Thrombus Formation By a Novel Plant Flavonoid
Plant-based flavonoids have been examined as inhibitors of β-coronavirus replication and as potential therapeutics for COVID19 based on their safety profile and widespread availability. SARS-CoV-2 viral replication is dependent on a cysteine protease known as 3CL protease, or main protease (Mpro), w...
Autores principales: | Yang, Moua, Lin, Lin, Scartelli, Christina, Chen, Da-Yuan, Patel, Anika, Bekendam, Roelof, Sun, Lijun, Saeed, Mohsan, Flaumenhaft, Robert |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology. Published by Elsevier Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8701548/ http://dx.doi.org/10.1182/blood-2021-153513 |
Ejemplares similares
-
Sars-Cov-2 Induced Endotheliopathy and the Impact on Clinical Outcomes in Critically Ill Pediatric Patients
por: Agarwal, Shreya, et al.
Publicado: (2021) -
Circulating Levels of Ang/Tie2 and VEGF-a Pathway Mediators Are Associated with Clinical Severity, Endothelial Barrier Disruption and Coagulation Activation in COVID-19
por: de Moraes, Carla Roberta Peachazepi, et al.
Publicado: (2021) -
The Deglycosylated Form of 1E12, a Monoclonal Anti-PF4 IgG, Strongly Inhibits Antibody-Triggered Cellular Activation in Vaccine-Induced Thrombotic Thrombocytopenia, and Is a Potential New Treatment for Vιττ
por: Vayne, Caroline, et al.
Publicado: (2021) -
Sars-Cov-2 Infection Promotes Endothelial Dysfunction and Thrombosis in a Mouse Model of COVID-19
por: Aiolfi, Roberto, et al.
Publicado: (2021) -
The Role of PF4 Antibodies in Pediatric Sars-Cov-2 Infections
por: Chiem, Meady, et al.
Publicado: (2021)