Association between Insufficient Interleukin-6 (IL-6) Inhibition and Worsening Outcomes in COVID-19 and Idiopathic Multicentric Castleman Disease (iMCD), and a Mathematical Model to Predict Optimal Dosing to Completely Block IL-6 Activity

Dysregulated inflammatory responses are characterized by inappropriate levels of inflammatory markers, speed of generation, degree, and major site of production, such as a vital organ. COVID-19 severity and mortality are strongly associated with interleukin (IL)-6 levels. High IL-6 levels are also o...

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Detalles Bibliográficos
Autores principales: Rossi, Jean-Francois, Chiang, Hao-Chun, Lu, Zhao-Yang, Levon, Kalle, van Rhee, Frits, Kanhai, Karan, Fajgenbaum, David C, Klein, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology. Published by Elsevier Inc. 2021
Materias:
803.Emerging Diagnostic Tools and Techniques
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8701554/
http://dx.doi.org/10.1182/blood-2021-150433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8701554/
http://dx.doi.org/10.1182/blood-2021-150433

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