Profound B-Cell Lymphopenia Is a Major Factor Predicting Poor Humoral Response after BNT162b2 mRNA Sars-Cov-2 Vaccines in Recipients of Allogeneic Hematopoietic Stem Cell Transplantation

Background Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection results in poor outcome in patients with hematologic malignancies. Moreover, the efficacy of anti-SARS-CoV-2 mRNA vaccines appears lower in immunocompromised patients, including recipients of allogeneic stem cell trans...

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Detalles Bibliográficos
Autores principales: Jullien, Maxime, Le Bourgeois, Amandine, Coste-Burel, Marianne, Peterlin, Pierre, Garnier, Alice, Audrain, Marie, Rimbert, Marie, Imbert, Berthe Marie, Drumel, Thomas, Le Gouill, Steven, Moreau, Philippe, Mahé, Béatrice, Dubruille, Viviane, Blin, Nicolas, Lok, Anne, Touzeau, Cyrille, Gastinne, Thomas, Tessoulin, Benoit, Vantyghem, Sophie, Béné, Marie C, Guillaume, Thierry, Chevallier, Patrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology. Published by Elsevier Inc. 2021
Materias:
722.Allogeneic Transplantation: Acute and Chronic GVHD, Immune Reconstitution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8701579/
http://dx.doi.org/10.1182/blood-2021-150439

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