Circulating Levels of Ang/Tie2 and VEGF-a Pathway Mediators Are Associated with Clinical Severity, Endothelial Barrier Disruption and Coagulation Activation in COVID-19

Background: the pathogenesis of severe COVID-19 involves the deregulated activation of different compartments of immunothrombosis, which are otherwise important for pathogen eradication and tissue repair. Coagulation activation, angiogenesis and alterations of endothelial barrier (EB) are elements o...

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Autores principales: de Moraes, Carla Roberta Peachazepi, de Borba Junior, Ivanio Teixeira, de Lima, Franciele, Barbosa, Mayck Silva, Huber, Stephany Cares, Palma, Andre C., Nunes, Thyago A., Ulaf, Raisa G., Ribeiro, Luciana C., Bernandes, Ana Flavia, Bombassaro, Bruna, Dertkigil, Sergio S., Moretti, Maria Luiza, Bizzacchi, Joyce Annichino, Mansour, Eli, Velloso, Lício Augusto, Maranhão Costa, Fábio Trindade, Orsi, Fernanda Andrade, De Paula, Erich V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology. Published by Elsevier Inc. 2021
Materias:
301.Vasculature, Endothelial Cells and Platelets: Basic and Translational
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8701641/
http://dx.doi.org/10.1182/blood-2021-152771

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