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Comparison of 6 equations for estimating glomerular filtration rate in a Chinese benign hypertensive nephrosclerosis population

Equations to estimate glomerular filtration rate (eGFR) are useful for monitoring tje renal status of benign hypertensive nephrosclerosis (BHN). This study aimed to compare the applicability of 6 equations (Cockcroft-Gault [CG] adjusted for body surface area, original modification of diet in renal d...

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Autores principales: Ke, Guibao, Xie, Zhibin, Xiao, Jie, Zhang, Yamei, Hu, Yao, Li, Bohou, Jiang, Nan, Chen, Xueqin, Liu, Shuangxin, Shi, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8701793/
https://www.ncbi.nlm.nih.gov/pubmed/34941129
http://dx.doi.org/10.1097/MD.0000000000028318
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author Ke, Guibao
Xie, Zhibin
Xiao, Jie
Zhang, Yamei
Hu, Yao
Li, Bohou
Jiang, Nan
Chen, Xueqin
Liu, Shuangxin
Shi, Wei
author_facet Ke, Guibao
Xie, Zhibin
Xiao, Jie
Zhang, Yamei
Hu, Yao
Li, Bohou
Jiang, Nan
Chen, Xueqin
Liu, Shuangxin
Shi, Wei
author_sort Ke, Guibao
collection PubMed
description Equations to estimate glomerular filtration rate (eGFR) are useful for monitoring tje renal status of benign hypertensive nephrosclerosis (BHN). This study aimed to compare the applicability of 6 equations (Cockcroft-Gault [CG] adjusted for body surface area, original modification of diet in renal disease [MDRD], American abbreviated MDRD, Chinese modified MDRD, Chinese abbreviated MDRD, and Chronic Kidney Disease Epidemiology [CKD-EPI]) to estimate GFR in a Chinese BHN population. A total of 179 patients diagnosed with BHN were enrolled. The GFR estimated by each equation was compared to the reference GFR (rGFR) measured using the dual plasma sampling technetium-labeled diethylenetriaminepentaacetic acid method. The Chinese modified and Chinese abbreviated MDRD equations overestimated the rGFR, while the CG, CG adjusted for body surface area, original MDRD, American abbreviated MDRD, and CKD-EPI equations underestimated the rGFR. The difference in performance between estimated GFR (eGFR) based on the American abbreviated MDRD equation and the rGFR was not statistically significant (P = .191), while differences in the others were statistically significant (P < .05). Furthermore, the advantages in deviation, absolute deviation, deviation degree, precision, and accuracy were also significantly different from those of the other equations. Our findings suggest that eGFR based on the American abbreviated MDRD equation is suitable for the Chinese BHN population.
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spelling pubmed-87017932021-12-27 Comparison of 6 equations for estimating glomerular filtration rate in a Chinese benign hypertensive nephrosclerosis population Ke, Guibao Xie, Zhibin Xiao, Jie Zhang, Yamei Hu, Yao Li, Bohou Jiang, Nan Chen, Xueqin Liu, Shuangxin Shi, Wei Medicine (Baltimore) 5200 Equations to estimate glomerular filtration rate (eGFR) are useful for monitoring tje renal status of benign hypertensive nephrosclerosis (BHN). This study aimed to compare the applicability of 6 equations (Cockcroft-Gault [CG] adjusted for body surface area, original modification of diet in renal disease [MDRD], American abbreviated MDRD, Chinese modified MDRD, Chinese abbreviated MDRD, and Chronic Kidney Disease Epidemiology [CKD-EPI]) to estimate GFR in a Chinese BHN population. A total of 179 patients diagnosed with BHN were enrolled. The GFR estimated by each equation was compared to the reference GFR (rGFR) measured using the dual plasma sampling technetium-labeled diethylenetriaminepentaacetic acid method. The Chinese modified and Chinese abbreviated MDRD equations overestimated the rGFR, while the CG, CG adjusted for body surface area, original MDRD, American abbreviated MDRD, and CKD-EPI equations underestimated the rGFR. The difference in performance between estimated GFR (eGFR) based on the American abbreviated MDRD equation and the rGFR was not statistically significant (P = .191), while differences in the others were statistically significant (P < .05). Furthermore, the advantages in deviation, absolute deviation, deviation degree, precision, and accuracy were also significantly different from those of the other equations. Our findings suggest that eGFR based on the American abbreviated MDRD equation is suitable for the Chinese BHN population. Lippincott Williams & Wilkins 2021-12-23 /pmc/articles/PMC8701793/ /pubmed/34941129 http://dx.doi.org/10.1097/MD.0000000000028318 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC), where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/)
spellingShingle 5200
Ke, Guibao
Xie, Zhibin
Xiao, Jie
Zhang, Yamei
Hu, Yao
Li, Bohou
Jiang, Nan
Chen, Xueqin
Liu, Shuangxin
Shi, Wei
Comparison of 6 equations for estimating glomerular filtration rate in a Chinese benign hypertensive nephrosclerosis population
title Comparison of 6 equations for estimating glomerular filtration rate in a Chinese benign hypertensive nephrosclerosis population
title_full Comparison of 6 equations for estimating glomerular filtration rate in a Chinese benign hypertensive nephrosclerosis population
title_fullStr Comparison of 6 equations for estimating glomerular filtration rate in a Chinese benign hypertensive nephrosclerosis population
title_full_unstemmed Comparison of 6 equations for estimating glomerular filtration rate in a Chinese benign hypertensive nephrosclerosis population
title_short Comparison of 6 equations for estimating glomerular filtration rate in a Chinese benign hypertensive nephrosclerosis population
title_sort comparison of 6 equations for estimating glomerular filtration rate in a chinese benign hypertensive nephrosclerosis population
topic 5200
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8701793/
https://www.ncbi.nlm.nih.gov/pubmed/34941129
http://dx.doi.org/10.1097/MD.0000000000028318
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