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Suboptimal Humoral and Cellular Immune Response to SARS-CoV-2 RNA Vaccination in Myeloma Patients Is Associated with Anti-CD38 and BCMA-Targeted Treatment
Background: Multiple myeloma (MM) patients are immunocompromised due to defects in humoral/cellular immunity and immunosuppressive therapy. Reports indicate that the antibody (Ab) response in MM after 1 dose of SARS-CoV-2 RNA vaccine is attenuated. The impact of treatment on cellular immunity after...
Autores principales: | Van Oekelen, Oliver, Agte, Sarita, Aleman, Adolfo, Upadhyaya, Bhaskar, Gleason, Charles R., Srivastava, Komal, Beach, Katherine F., Tuballes, Kevin, Kappes, Katerina, Mouhieddine, Tarek H., Wang, Bo, Kim-Schulze, Seunghee, Chari, Ajai, Gnjatic, Sacha, Bhardwaj, Nina, Brown, Brian D., Merad, Miriam, Cordon-Cardo, Carlos, Krammer, Florian, Jagannath, Sundar, Simon, Viviana, Wajnberg, Ania, Parekh, Samir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology. Published by Elsevier Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8701831/ https://www.ncbi.nlm.nih.gov/pubmed/34499154 http://dx.doi.org/10.1182/blood-2021-152365 |
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