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Choroidal metastasis with retinal detachment: A case report

RATIONALE: Breast carcinoma is the most common primary source of choroidal metastasis (CM). In the present case, esophageal cancer was the primary tumour, brain metastasis occurred, and CM occurred later in the left eye with 2 retinal detachments, which is very rare. PATIENT CONCERNS: A 62-year-old...

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Autores principales: Lin, Shu-Hua, Xu, Yong-Gen, Zhao, Jing-Hua, Cui, Hong, Jin, Hua, Jia, Yu-Jie, Zhao, Jian, Li, Ying-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702016/
https://www.ncbi.nlm.nih.gov/pubmed/34941041
http://dx.doi.org/10.1097/MD.0000000000028009
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author Lin, Shu-Hua
Xu, Yong-Gen
Zhao, Jing-Hua
Cui, Hong
Jin, Hua
Jia, Yu-Jie
Zhao, Jian
Li, Ying-Jun
author_facet Lin, Shu-Hua
Xu, Yong-Gen
Zhao, Jing-Hua
Cui, Hong
Jin, Hua
Jia, Yu-Jie
Zhao, Jian
Li, Ying-Jun
author_sort Lin, Shu-Hua
collection PubMed
description RATIONALE: Breast carcinoma is the most common primary source of choroidal metastasis (CM). In the present case, esophageal cancer was the primary tumour, brain metastasis occurred, and CM occurred later in the left eye with 2 retinal detachments, which is very rare. PATIENT CONCERNS: A 62-year-old man complained of a sudden decrease in visual acuity consisting of a small shadow in front of his left eye with a sensation of covered vision after 1 cycle of systemic chemotherapy and radiotherapy for resected esophageal cancer with brain metastasis. Fundus examination revealed exudative retinal detachment without retinal tears. CM with exudative retinal detachment was also considered. The patient refused further treatment. After the second cycle of chemotherapy, there were no significant changes in the retina and visual acuity improved. However, after craniocerebral surgery for brain metastasis, the visual acuity decreased again and showed 3 choroidal masses with macular involvement and retinal detachment but without retinal tears. DIAGNOSIS: The final diagnosis was CM with retinal detachment. INTERVENTIONS: The patient was advised to undergo enucleation of the left eye during the second retinal detachment, but he refused. OUTCOMES: Two months after the second retinal detachment, the patient died of systemic metastases. LESSONS: It is important to consider CM when the first retinal detachment and known cancer are diagnosed. At present, it is necessary to develop a standardised treatment plan as well as a multidisciplinary approach to early diagnosis, combined treatment, and timely intervention for such cases.
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spelling pubmed-87020162021-12-27 Choroidal metastasis with retinal detachment: A case report Lin, Shu-Hua Xu, Yong-Gen Zhao, Jing-Hua Cui, Hong Jin, Hua Jia, Yu-Jie Zhao, Jian Li, Ying-Jun Medicine (Baltimore) 5800 RATIONALE: Breast carcinoma is the most common primary source of choroidal metastasis (CM). In the present case, esophageal cancer was the primary tumour, brain metastasis occurred, and CM occurred later in the left eye with 2 retinal detachments, which is very rare. PATIENT CONCERNS: A 62-year-old man complained of a sudden decrease in visual acuity consisting of a small shadow in front of his left eye with a sensation of covered vision after 1 cycle of systemic chemotherapy and radiotherapy for resected esophageal cancer with brain metastasis. Fundus examination revealed exudative retinal detachment without retinal tears. CM with exudative retinal detachment was also considered. The patient refused further treatment. After the second cycle of chemotherapy, there were no significant changes in the retina and visual acuity improved. However, after craniocerebral surgery for brain metastasis, the visual acuity decreased again and showed 3 choroidal masses with macular involvement and retinal detachment but without retinal tears. DIAGNOSIS: The final diagnosis was CM with retinal detachment. INTERVENTIONS: The patient was advised to undergo enucleation of the left eye during the second retinal detachment, but he refused. OUTCOMES: Two months after the second retinal detachment, the patient died of systemic metastases. LESSONS: It is important to consider CM when the first retinal detachment and known cancer are diagnosed. At present, it is necessary to develop a standardised treatment plan as well as a multidisciplinary approach to early diagnosis, combined treatment, and timely intervention for such cases. Lippincott Williams & Wilkins 2021-12-23 /pmc/articles/PMC8702016/ /pubmed/34941041 http://dx.doi.org/10.1097/MD.0000000000028009 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/)
spellingShingle 5800
Lin, Shu-Hua
Xu, Yong-Gen
Zhao, Jing-Hua
Cui, Hong
Jin, Hua
Jia, Yu-Jie
Zhao, Jian
Li, Ying-Jun
Choroidal metastasis with retinal detachment: A case report
title Choroidal metastasis with retinal detachment: A case report
title_full Choroidal metastasis with retinal detachment: A case report
title_fullStr Choroidal metastasis with retinal detachment: A case report
title_full_unstemmed Choroidal metastasis with retinal detachment: A case report
title_short Choroidal metastasis with retinal detachment: A case report
title_sort choroidal metastasis with retinal detachment: a case report
topic 5800
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702016/
https://www.ncbi.nlm.nih.gov/pubmed/34941041
http://dx.doi.org/10.1097/MD.0000000000028009
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