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The Effects of Sequence Length and Composition of Random Sequence Peptides on the Growth of E. coli Cells

We study the potential for the de novo evolution of genes from random nucleotide sequences using libraries of E. coli expressing random sequence peptides. We assess the effects of such peptides on cell growth by monitoring frequency changes in individual clones in a complex library through four seri...

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Detalles Bibliográficos
Autores principales: Castro, Johana F., Tautz, Diethard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702183/
https://www.ncbi.nlm.nih.gov/pubmed/34946861
http://dx.doi.org/10.3390/genes12121913