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Quality of Life in Adults with Metabolic Dysfunction-Associated Fatty Liver Disease

The aims of this study were as follows: to investigate the association between metabolic dysfunction-associated fatty liver disease (MAFLD) and health-related quality of life (HRQoL), to evaluate whether stress perception and mental health among patients with MAFLD affect HRQoL, and to identify the...

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Autores principales: Hwang, Tae-In, Han, A-Lum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702216/
https://www.ncbi.nlm.nih.gov/pubmed/34948754
http://dx.doi.org/10.3390/ijerph182413145
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author Hwang, Tae-In
Han, A-Lum
author_facet Hwang, Tae-In
Han, A-Lum
author_sort Hwang, Tae-In
collection PubMed
description The aims of this study were as follows: to investigate the association between metabolic dysfunction-associated fatty liver disease (MAFLD) and health-related quality of life (HRQoL), to evaluate whether stress perception and mental health among patients with MAFLD affect HRQoL, and to identify the underrated burden on MAFLD patients. Nationwide data from the 5th Korean National Health and Nutrition Examination Survey (KNHANES V, 2010 to 2012) were used. MAFLD was defined by a fatty liver index (FLI) of ≥60, and the EuroQol-5D (EQ-5D) was used to assess HRQoL. Logistic regression analysis and odds ratios (ORs) were used to determine the associations of MAFLD with stress, mental health, and HRQoL. Previous suicidal impulse was not found to be significantly associated with HRQoL. The risk of MAFLD increased 1.265-fold with an increase in stress levels based on the stress perception rate (confidence index (CI): 1.046–1.530; p < 0.05), while it increased 1.091-fold with a 1-point decrease in the EQ-5D score (CI: 1.019–1.169; p < 0.05). HRQoL impairment and stress levels are associated with MAFLD. It is important to evaluate stress levels among MAFLD patients and implement stress management and HRQoL improvement strategies.
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spelling pubmed-87022162021-12-24 Quality of Life in Adults with Metabolic Dysfunction-Associated Fatty Liver Disease Hwang, Tae-In Han, A-Lum Int J Environ Res Public Health Article The aims of this study were as follows: to investigate the association between metabolic dysfunction-associated fatty liver disease (MAFLD) and health-related quality of life (HRQoL), to evaluate whether stress perception and mental health among patients with MAFLD affect HRQoL, and to identify the underrated burden on MAFLD patients. Nationwide data from the 5th Korean National Health and Nutrition Examination Survey (KNHANES V, 2010 to 2012) were used. MAFLD was defined by a fatty liver index (FLI) of ≥60, and the EuroQol-5D (EQ-5D) was used to assess HRQoL. Logistic regression analysis and odds ratios (ORs) were used to determine the associations of MAFLD with stress, mental health, and HRQoL. Previous suicidal impulse was not found to be significantly associated with HRQoL. The risk of MAFLD increased 1.265-fold with an increase in stress levels based on the stress perception rate (confidence index (CI): 1.046–1.530; p < 0.05), while it increased 1.091-fold with a 1-point decrease in the EQ-5D score (CI: 1.019–1.169; p < 0.05). HRQoL impairment and stress levels are associated with MAFLD. It is important to evaluate stress levels among MAFLD patients and implement stress management and HRQoL improvement strategies. MDPI 2021-12-13 /pmc/articles/PMC8702216/ /pubmed/34948754 http://dx.doi.org/10.3390/ijerph182413145 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hwang, Tae-In
Han, A-Lum
Quality of Life in Adults with Metabolic Dysfunction-Associated Fatty Liver Disease
title Quality of Life in Adults with Metabolic Dysfunction-Associated Fatty Liver Disease
title_full Quality of Life in Adults with Metabolic Dysfunction-Associated Fatty Liver Disease
title_fullStr Quality of Life in Adults with Metabolic Dysfunction-Associated Fatty Liver Disease
title_full_unstemmed Quality of Life in Adults with Metabolic Dysfunction-Associated Fatty Liver Disease
title_short Quality of Life in Adults with Metabolic Dysfunction-Associated Fatty Liver Disease
title_sort quality of life in adults with metabolic dysfunction-associated fatty liver disease
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702216/
https://www.ncbi.nlm.nih.gov/pubmed/34948754
http://dx.doi.org/10.3390/ijerph182413145
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