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The effect of non-pharmacological interventions on psychological stress and quality of life of parents of children with retinoblastoma: A protocol for systematic review and meta-analysis
BACKGROUND: Retinoblastoma is the most common malignant tumor in infancy and early childhood. Due to the high incidences of intracranial metastasis and distant metastasis, retinoblastoma not only threatens the life of affected children, but also brings heavy mental stress to their parents. A strong...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702223/ https://www.ncbi.nlm.nih.gov/pubmed/34941063 http://dx.doi.org/10.1097/MD.0000000000028148 |
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author | Wu, Lei Xiang, Xitao Guo, Hong Tan, Hui |
author_facet | Wu, Lei Xiang, Xitao Guo, Hong Tan, Hui |
author_sort | Wu, Lei |
collection | PubMed |
description | BACKGROUND: Retinoblastoma is the most common malignant tumor in infancy and early childhood. Due to the high incidences of intracranial metastasis and distant metastasis, retinoblastoma not only threatens the life of affected children, but also brings heavy mental stress to their parents. A strong mental stress often leads to anxiety, depression, and other adverse emotions, which is very unfavorable to the treatment and prognosis by generating great psychological pressure and reducing the quality of life of the family. Reducing the psychological stress of the parents and improving the quality of life of the family are beneficial to the treatment and prognosis of retinoblastoma in children. However, there are no recommended non-pharmacological therapies to reduce the psychological stress and improve the quality of life of the parents of children with retinoblastoma. This study aims to evaluate the effects of non-pharmacological therapies on psychological stress and quality of life of parents of children with retinoblastoma through a meta-analysis, thus providing clinical evidence. METHODS: Randomized controlled trials reporting the effects of non-pharmacological therapies on psychological stress and quality of life of parents of children with retinoblastoma published before 2021 November will be searched in online databases, including the China National Knowledge Infrastructure, Wanfang, Chinese Scientific Journal Database, China Biomedical Literature Database, PubMed, Embase, The Cochrane Library, and Web of Science databases. The Cochrane Quality Assessment Manual will be used to assess the quality of the included literatures. Meta-analysis will be performed using Revman 5.4 software. RESULTS: This study will evaluate the effects of non-pharmacological therapies on psychological stress and quality of life of parents of children with retinoblastoma via grading anxiety scores, depression scores, and quality-of-life scores. CONCLUSION: This study will provide a reliable evidence-based basis for non-pharmacological interventions on parents of children with retinoblastoma. ETHICS AND DISSEMINATION: Ethical approval was not required for this study. The systematic review will be published in a peer-reviewed journal, presented at conferences, and shared on social media platforms. This review would be disseminated in a peer-reviewed journal or conference presentations. OSF REGISTRATION NUMBER: |
format | Online Article Text |
id | pubmed-8702223 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-87022232021-12-27 The effect of non-pharmacological interventions on psychological stress and quality of life of parents of children with retinoblastoma: A protocol for systematic review and meta-analysis Wu, Lei Xiang, Xitao Guo, Hong Tan, Hui Medicine (Baltimore) 3800 BACKGROUND: Retinoblastoma is the most common malignant tumor in infancy and early childhood. Due to the high incidences of intracranial metastasis and distant metastasis, retinoblastoma not only threatens the life of affected children, but also brings heavy mental stress to their parents. A strong mental stress often leads to anxiety, depression, and other adverse emotions, which is very unfavorable to the treatment and prognosis by generating great psychological pressure and reducing the quality of life of the family. Reducing the psychological stress of the parents and improving the quality of life of the family are beneficial to the treatment and prognosis of retinoblastoma in children. However, there are no recommended non-pharmacological therapies to reduce the psychological stress and improve the quality of life of the parents of children with retinoblastoma. This study aims to evaluate the effects of non-pharmacological therapies on psychological stress and quality of life of parents of children with retinoblastoma through a meta-analysis, thus providing clinical evidence. METHODS: Randomized controlled trials reporting the effects of non-pharmacological therapies on psychological stress and quality of life of parents of children with retinoblastoma published before 2021 November will be searched in online databases, including the China National Knowledge Infrastructure, Wanfang, Chinese Scientific Journal Database, China Biomedical Literature Database, PubMed, Embase, The Cochrane Library, and Web of Science databases. The Cochrane Quality Assessment Manual will be used to assess the quality of the included literatures. Meta-analysis will be performed using Revman 5.4 software. RESULTS: This study will evaluate the effects of non-pharmacological therapies on psychological stress and quality of life of parents of children with retinoblastoma via grading anxiety scores, depression scores, and quality-of-life scores. CONCLUSION: This study will provide a reliable evidence-based basis for non-pharmacological interventions on parents of children with retinoblastoma. ETHICS AND DISSEMINATION: Ethical approval was not required for this study. The systematic review will be published in a peer-reviewed journal, presented at conferences, and shared on social media platforms. This review would be disseminated in a peer-reviewed journal or conference presentations. OSF REGISTRATION NUMBER: Lippincott Williams & Wilkins 2021-12-23 /pmc/articles/PMC8702223/ /pubmed/34941063 http://dx.doi.org/10.1097/MD.0000000000028148 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) |
spellingShingle | 3800 Wu, Lei Xiang, Xitao Guo, Hong Tan, Hui The effect of non-pharmacological interventions on psychological stress and quality of life of parents of children with retinoblastoma: A protocol for systematic review and meta-analysis |
title | The effect of non-pharmacological interventions on psychological stress and quality of life of parents of children with retinoblastoma: A protocol for systematic review and meta-analysis |
title_full | The effect of non-pharmacological interventions on psychological stress and quality of life of parents of children with retinoblastoma: A protocol for systematic review and meta-analysis |
title_fullStr | The effect of non-pharmacological interventions on psychological stress and quality of life of parents of children with retinoblastoma: A protocol for systematic review and meta-analysis |
title_full_unstemmed | The effect of non-pharmacological interventions on psychological stress and quality of life of parents of children with retinoblastoma: A protocol for systematic review and meta-analysis |
title_short | The effect of non-pharmacological interventions on psychological stress and quality of life of parents of children with retinoblastoma: A protocol for systematic review and meta-analysis |
title_sort | effect of non-pharmacological interventions on psychological stress and quality of life of parents of children with retinoblastoma: a protocol for systematic review and meta-analysis |
topic | 3800 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702223/ https://www.ncbi.nlm.nih.gov/pubmed/34941063 http://dx.doi.org/10.1097/MD.0000000000028148 |
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