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The Effect of Terpenoid Natural Chinese Medicine Molecular Compound on Lung Cancer Treatment

Among all malignant tumors in the whole universe, the incidence and mortality of lung cancer disease rank first. Especially in the past few years, the occurrence of lung cancer in the urban population has continued to increase, which seriously threatens the lives and health of people. Among the many...

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Autores principales: Sun, Heng, Zhang, Lijia, Sui, Bowen, Li, Yu, Yan, Jun, Wang, Peng, Wang, Ye, Liu, Songjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702311/
https://www.ncbi.nlm.nih.gov/pubmed/34956377
http://dx.doi.org/10.1155/2021/3730963
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author Sun, Heng
Zhang, Lijia
Sui, Bowen
Li, Yu
Yan, Jun
Wang, Peng
Wang, Ye
Liu, Songjiang
author_facet Sun, Heng
Zhang, Lijia
Sui, Bowen
Li, Yu
Yan, Jun
Wang, Peng
Wang, Ye
Liu, Songjiang
author_sort Sun, Heng
collection PubMed
description Among all malignant tumors in the whole universe, the incidence and mortality of lung cancer disease rank first. Especially in the past few years, the occurrence of lung cancer in the urban population has continued to increase, which seriously threatens the lives and health of people. Among the many treatments for lung cancer, chemotherapy is the best one, but traditional chemotherapy has low specificity and drug resistance. To address the above issue, this study reviews the five biological pathways that common terpenoid compounds in medicinal plants interfere with the occurrence and development of lung cancer: cell proliferation, cell apoptosis, cell autophagy, cell invasion, metastasis, and immune mechanism regulation. In addition, the mechanism of the terpenoid natural traditional Chinese medicine monomer compound combined with Western medicine in the multipathway antilung cancer is summarized.
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spelling pubmed-87023112021-12-24 The Effect of Terpenoid Natural Chinese Medicine Molecular Compound on Lung Cancer Treatment Sun, Heng Zhang, Lijia Sui, Bowen Li, Yu Yan, Jun Wang, Peng Wang, Ye Liu, Songjiang Evid Based Complement Alternat Med Review Article Among all malignant tumors in the whole universe, the incidence and mortality of lung cancer disease rank first. Especially in the past few years, the occurrence of lung cancer in the urban population has continued to increase, which seriously threatens the lives and health of people. Among the many treatments for lung cancer, chemotherapy is the best one, but traditional chemotherapy has low specificity and drug resistance. To address the above issue, this study reviews the five biological pathways that common terpenoid compounds in medicinal plants interfere with the occurrence and development of lung cancer: cell proliferation, cell apoptosis, cell autophagy, cell invasion, metastasis, and immune mechanism regulation. In addition, the mechanism of the terpenoid natural traditional Chinese medicine monomer compound combined with Western medicine in the multipathway antilung cancer is summarized. Hindawi 2021-12-16 /pmc/articles/PMC8702311/ /pubmed/34956377 http://dx.doi.org/10.1155/2021/3730963 Text en Copyright © 2021 Heng Sun et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Sun, Heng
Zhang, Lijia
Sui, Bowen
Li, Yu
Yan, Jun
Wang, Peng
Wang, Ye
Liu, Songjiang
The Effect of Terpenoid Natural Chinese Medicine Molecular Compound on Lung Cancer Treatment
title The Effect of Terpenoid Natural Chinese Medicine Molecular Compound on Lung Cancer Treatment
title_full The Effect of Terpenoid Natural Chinese Medicine Molecular Compound on Lung Cancer Treatment
title_fullStr The Effect of Terpenoid Natural Chinese Medicine Molecular Compound on Lung Cancer Treatment
title_full_unstemmed The Effect of Terpenoid Natural Chinese Medicine Molecular Compound on Lung Cancer Treatment
title_short The Effect of Terpenoid Natural Chinese Medicine Molecular Compound on Lung Cancer Treatment
title_sort effect of terpenoid natural chinese medicine molecular compound on lung cancer treatment
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702311/
https://www.ncbi.nlm.nih.gov/pubmed/34956377
http://dx.doi.org/10.1155/2021/3730963
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