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The Effect of Terpenoid Natural Chinese Medicine Molecular Compound on Lung Cancer Treatment
Among all malignant tumors in the whole universe, the incidence and mortality of lung cancer disease rank first. Especially in the past few years, the occurrence of lung cancer in the urban population has continued to increase, which seriously threatens the lives and health of people. Among the many...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702311/ https://www.ncbi.nlm.nih.gov/pubmed/34956377 http://dx.doi.org/10.1155/2021/3730963 |
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author | Sun, Heng Zhang, Lijia Sui, Bowen Li, Yu Yan, Jun Wang, Peng Wang, Ye Liu, Songjiang |
author_facet | Sun, Heng Zhang, Lijia Sui, Bowen Li, Yu Yan, Jun Wang, Peng Wang, Ye Liu, Songjiang |
author_sort | Sun, Heng |
collection | PubMed |
description | Among all malignant tumors in the whole universe, the incidence and mortality of lung cancer disease rank first. Especially in the past few years, the occurrence of lung cancer in the urban population has continued to increase, which seriously threatens the lives and health of people. Among the many treatments for lung cancer, chemotherapy is the best one, but traditional chemotherapy has low specificity and drug resistance. To address the above issue, this study reviews the five biological pathways that common terpenoid compounds in medicinal plants interfere with the occurrence and development of lung cancer: cell proliferation, cell apoptosis, cell autophagy, cell invasion, metastasis, and immune mechanism regulation. In addition, the mechanism of the terpenoid natural traditional Chinese medicine monomer compound combined with Western medicine in the multipathway antilung cancer is summarized. |
format | Online Article Text |
id | pubmed-8702311 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-87023112021-12-24 The Effect of Terpenoid Natural Chinese Medicine Molecular Compound on Lung Cancer Treatment Sun, Heng Zhang, Lijia Sui, Bowen Li, Yu Yan, Jun Wang, Peng Wang, Ye Liu, Songjiang Evid Based Complement Alternat Med Review Article Among all malignant tumors in the whole universe, the incidence and mortality of lung cancer disease rank first. Especially in the past few years, the occurrence of lung cancer in the urban population has continued to increase, which seriously threatens the lives and health of people. Among the many treatments for lung cancer, chemotherapy is the best one, but traditional chemotherapy has low specificity and drug resistance. To address the above issue, this study reviews the five biological pathways that common terpenoid compounds in medicinal plants interfere with the occurrence and development of lung cancer: cell proliferation, cell apoptosis, cell autophagy, cell invasion, metastasis, and immune mechanism regulation. In addition, the mechanism of the terpenoid natural traditional Chinese medicine monomer compound combined with Western medicine in the multipathway antilung cancer is summarized. Hindawi 2021-12-16 /pmc/articles/PMC8702311/ /pubmed/34956377 http://dx.doi.org/10.1155/2021/3730963 Text en Copyright © 2021 Heng Sun et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Sun, Heng Zhang, Lijia Sui, Bowen Li, Yu Yan, Jun Wang, Peng Wang, Ye Liu, Songjiang The Effect of Terpenoid Natural Chinese Medicine Molecular Compound on Lung Cancer Treatment |
title | The Effect of Terpenoid Natural Chinese Medicine Molecular Compound on Lung Cancer Treatment |
title_full | The Effect of Terpenoid Natural Chinese Medicine Molecular Compound on Lung Cancer Treatment |
title_fullStr | The Effect of Terpenoid Natural Chinese Medicine Molecular Compound on Lung Cancer Treatment |
title_full_unstemmed | The Effect of Terpenoid Natural Chinese Medicine Molecular Compound on Lung Cancer Treatment |
title_short | The Effect of Terpenoid Natural Chinese Medicine Molecular Compound on Lung Cancer Treatment |
title_sort | effect of terpenoid natural chinese medicine molecular compound on lung cancer treatment |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702311/ https://www.ncbi.nlm.nih.gov/pubmed/34956377 http://dx.doi.org/10.1155/2021/3730963 |
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