Plasma Exosomal Mir-423-5p Is Involved in the Occurrence and Development of Bicuspid Aortopathy via TGF-β/SMAD2 Pathway

Objectives: Patients with bicuspid aortic valve (BAV) are at increased risk for ascending aortic dilation (AAD). Our study was aimed at systemically analyzing the expression profile and mechanism of circulating plasma exosomal microRNAs (miRNAs) related to BAV and AAD. Methods: We isolated plasma ex...

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Detalles Bibliográficos
Autores principales: Zhang, Hongqiang, Liu, Dingqian, Zhu, Shichao, Wang, Fanshun, Sun, Xiaoning, Yang, Shouguo, Wang, Chunsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702998/
https://www.ncbi.nlm.nih.gov/pubmed/34955881
http://dx.doi.org/10.3389/fphys.2021.759035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8702998/
https://www.ncbi.nlm.nih.gov/pubmed/34955881
http://dx.doi.org/10.3389/fphys.2021.759035

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