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Assessment of Drug Proarrhythmicity Using Artificial Neural Networks With in silico Deterministic Model Outputs

As part of the Comprehensive in vitro Proarrhythmia Assay initiative, methodologies for predicting the occurrence of drug-induced torsade de pointes via computer simulations have been developed and verified recently. However, their predictive performance still requires improvement. Herein, we propos...

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Detalles Bibliográficos
Autores principales: Yoo, Yedam, Marcellinus, Aroli, Jeong, Da Un, Kim, Ki-Suk, Lim, Ki Moo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8703011/
https://www.ncbi.nlm.nih.gov/pubmed/34955882
http://dx.doi.org/10.3389/fphys.2021.761691